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Proteins/UNIPROT:P19623
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine..
Function from UniProtKB (P19623), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
300 statements
300 statements · 6 reference databases · Subject: SRM · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
putrescine+S-adenosylmethioninamineS-methyl-5'-thioadenosine+proton+spermidine
Catalysed by SRM
Reaction pageLeft to rightBalancedEC 2.5.1.16cytosol
Human-GEM MAR04075CC BY 4.0Reference data
S-adenosylmethioninamine+spermidineS-methyl-5'-thioadenosine+proton+CHEBI:15746
Catalysed by SMS
4 names
Resolves to: SRM
Reaction pageLeft to rightBalancedEC 2.5.1.16, 2.5.1.22cytosol
Human-GEM MAR04077CC BY 4.0Reference data
S-adenosyl 3-(methylsulfanyl)propylamine+putrescineS-methyl-5'-thioadenosine+spermidine+hydron
Catalysed by SRM
Reaction pageDirection not assertedBalanced
Rhea RHEA:12721CC BY 4.0Reference data