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Proteins/UNIPROT:Q56NI9
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3..
Function from UniProtKB (Q56NI9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
24 statements
24 statements · 6 reference databases · Subject: ESCO2 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, WikiPathways
3 reactions
butanoyl-CoA+(S)-carnitinebutanoyl-CoA+(S)-carnitine
Transported by OXSM or SLC33A1 or ESCO2
Reaction pageReversibleBalancedmitochondrial matrix, cytosol
Human-GEM MAR00158CC BY 4.0Reference data
CHEBI:1146900+proton+MAM02538cCHEBI:15351+CHEBI:15650
Catalysed by LPCAT2
6 names
Resolves to: ESCO2
Reaction pageReversibleBalancedEC 2.3.1.-cytosol
Human-GEM MAR01088CC BY 4.0Reference data
L-lysyl-[protein]+acetyl-CoAN(6)-acetyl-L-lysyl-[protein]+coenzyme A(4-)+hydron
Catalysed by HAT1 or CLOCK or TAF1 or BLOC1S1 or GTF2B or EP300 or NCOA1 or ESCO2 or ESCO1 or KAT6B or CREBBP or KAT6A and 12 more alternatives
Reaction pageReversibleBalance undeterminable
Rhea RHEA:45948CC BY 4.0Reference data