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Proteins/UNIPROT:Q9ULV0
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. Required for proper localization of bile salt export pump ABCB11 at the apical/canalicular plasma membrane of hepatocytes..
Function from UniProtKB (Q9ULV0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
71 statements
71 statements · 4 reference databases · Subject: MYO5B · Sources: Hetionet, Human-GEM, Reactome, WikiPathways
39 reactions
MAM00740x+CHEBI:1146900MAM00836x+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR01168CC BY 4.0Reference data
MAM00741x+CHEBI:1146900MAM00838x+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
2 names
Resolves to: MYO5B
MAM00420x+CHEBI:1146900MAM00421x+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR01260CC BY 4.0Reference data
MAM00846x+CHEBI:1146900MAM00688x+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR01277CC BY 4.0Reference data
MAM00584x+CHEBI:1146900CHEBI:15351+MAM02650x
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR01294CC BY 4.0Reference data
MAM00401x+CHEBI:1146900+waterCHEBI:15351+5proton+MAM02652x
Reaction pageLeft to rightUnbalancedEC 2.3.1.16peroxisome
Human-GEM MAR01301CC BY 4.0Reference data
3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA+CHEBI:1146900CHEBI:15519+propionyl-CoA
Catalysed by ACAA1 or SCP2 or MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.176, 2.3.1.16peroxisome
Human-GEM MAR01652CC BY 4.0Reference data
MAM00758cMAM00758m
Transported by ACAA1 or HADHB or MYO5B or ACAA2
Reaction pageReversibleBalancedEC 2.3.1.176, 2.3.1.16cytosol, mitochondrial matrix
Human-GEM MAR01694CC BY 4.0Reference data
MAM00754x+CHEBI:1146900CHEBI:28701+propionyl-CoA
Catalysed by ACAA1 or SCP2 or MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.176peroxisome
Human-GEM MAR01710CC BY 4.0Reference data
MAM00853x+CHEBI:1146900(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR02411CC BY 4.0Reference data
3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA+CHEBI:1146900(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA+CHEBI:15351
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR02513CC BY 4.0Reference data
3-oxohexacosanoyl-CoA+CHEBI:1146900CHEBI:15351+tetracosanoyl-CoA
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03060CC BY 4.0Reference data