Compound

N(1)-acetylspermine

Trication of N1-acetylspermine arising from protonation of the one primary and two secondary amino groups; major species at pH 7.3.

Definition from ChEBI (CHEBI:58101), read 2026-09-23. CC BY 4.0.

CHEBI:58101ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of N(1)-acetylspermine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, cation
Formula: C12H31N4O
Mass: 247.407 g/mol
Charge: +3
InChIKey: GUNURVWAJRRUAV-UHFFFAOYSA-Q
SMILES: CC(=O)NCCC[NH2+]CCCC[NH2+]CCC[NH3+]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

2 statements

2 statements · 1 reference database · Subject: N(1)-acetylspermine · Sources: Rhea

Order

N(1)-acetylspermine is a substrate of PAOXProteinRhea RHEA:25800Inferred only
N(1)-acetylspermine is a substrate of SAT1ProteinRhea RHEA:33099Inferred only

Reactions

5 reactions

N(1)-acetylspermine+dioxygen+waterN(1)-acetylspermidine+3-aminopropanal+hydrogen peroxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16133CC BY 4.0Reference data
N(1)-acetylspermine+dioxygen+water3-acetamidopropanal+spermidine+hydrogen peroxide
Catalysed by PAOX
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:25800CC BY 4.0Reference data
N(1)-acetylspermine+dioxygen+waterCHEBI:58858+propane-1,3-diamine+hydrogen peroxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:25996CC BY 4.0Reference data
spermine+acetyl-CoAN(1)-acetylspermine+coenzyme A(4-)+hydron
Catalysed by SAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33099CC BY 4.0Reference data
N(1)-acetylspermine+waterspermine+acetate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:51896CC BY 4.0Reference data

Other names

3 names

Resolves to: N(1)-acetylspermine

Also called: N(1)-acetylsperminium tricationN1-acetylsperminium trication
Systematic name: N-(3-acetamidopropyl)-N'-(3-azaniumylpropyl)butane-1,4-diaminium