hydroxyacetone

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

56 compounds within 3 steps: 2 in 1, 4 in 2, 50 in 3

One step

propane-1,2-diolReach from here →
1. aldose reductase (hydroxyacetone)
Catalysed by AKR7A2, AKR1A1, AKR1B1cytosol
methylglyoxalReach from here →
1. cytochrome P450 (hydroxyacetone)
Catalysed by CYP2E1cytosol

Two steps

pyruvateReach from here →
1. cytochrome P450 (hydroxyacetone)
2. 2-Oxopropanal:NADP+ oxidoreductase
Catalysed by CYP2E1cytosol
(R)-lactaldehydeReach from here →
1. cytochrome P450 (hydroxyacetone)
2. (R)-Lactaldehyde:NAD+ oxidoreductase
Catalysed by CYP2E1cytosolOne of 3 routes
(R)-S-lactoylglutathioneReach from here →
1. cytochrome P450 (hydroxyacetone)

Three steps

2-hydroxybutyric acidReach from here →
Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes
acetoacetateReach from here →

(R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)

Catalysed by CYP2E1, GLO1, GLOD4cytosolOne of 2 routes

dihydroxyacetone phosphateReach from here →

Catalysed by CYP2E1, TPI1cytosol

Catalysed by CYP2E1

cytosol, mitochondrial matrix

One of 4 routes

beta-D-fructose 1-phosphateReach from here →

Catalysed by CYP2E1, TPI1, ALDOBcytosol

acetylpyruvateReach from here →

Catalysed by CYP2E1, FAHD1cytosol

all-trans-retinoic acidReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

(S)-malateReach from here →

Catalysed by CYP2E1, ME2cytosolOne of 2 routes

(R)-lactateReach from here →

Catalysed by CYP2E1, GLO1, GLOD4, HAGHcytosol

dihydroxyacetoneReach from here →

Catalysed by CYP2E1, TPI1, TKFCcytosol

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by CYP2E1, AGXT2cytosol, mitochondrial matrix

oxaloacetateReach from here →

Catalysed by CYP2E1, PCcytosol, mitochondrial matrixOne of 3 routes

(S)-lactateReach from here →

Catalysed by CYP2E1, LDHA, LDHB, LDHC and 2 morecytosol

2-oxobutanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

2-oxoglutaramateReach from here →

Catalysed by CYP2E1, KYAT1cytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by CYP2E1, FAHD1cytosol

CHEBI:16856Reach from here →

Catalysed by CYP2E1, GLO1, GLOD4, HAGH and 1 morecytosolOne of 3 routes

(R)-3-hydroxybutyric acidReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

3-hydroxypyruvateReach from here →

Catalysed by CYP2E1, AGXTcytosol

aceneuramateReach from here →

Catalysed by CYP2E1, NPLcytosol

5'-deoxyadenosineReach from here →

Catalysed by CYP2E1, TYW1B, TYW1cytosol

dTDPReach from here →

Catalysed by CYP2E1, PKM, PKLRcytosol

5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

5-(3,3'-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

5-(3-methylguanidino)-2-oxopentanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

acetateReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 2 morecytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by CYP2E1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

3-hydroxypyruvic acidReach from here →

Catalysed by CYP2E1, AGXTcytosolOne of 2 routes

beta-D-fructose 1,6-bisphosphateReach from here →

Catalysed by CYP2E1, TPI1, ALDOA, ALDOB and 1 morecytosol

3-oxopropanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

D-serineReach from here →

Catalysed by CYP2E1, SRRcytosol

(R)-lactic acidReach from here →

Catalysed by CYP2E1, GLO1, GLOD4, HAGH and 1 morecytosolOne of 5 routes

(S)-lactic acidReach from here →

Catalysed by CYP2E1, LDHB, LDHAL6Bcytosol, mitochondrial matrixOne of 5 routes

2-iminopropanoateReach from here →

Catalysed by CYP2E1, RIDAcytosol

phosphoenolpyruvic acidReach from here →

Catalysed by CYP2E1, PKM, PKLRcytosol

N-acetyl-beta-neuraminic acidReach from here →

Catalysed by CYP2E1, NPLcytosol

a 3-acylpyruvateReach from here →

Catalysed by CYP2E1, FAHD1cytosol

a 1-acylglycerone 3-phosphateReach from here →

Catalysed by CYP2E1, TPI1, GNPATcytosol

2-oxo-3-sulfanylpropanoateReach from here →

Catalysed by CYP2E1, MPSTcytosol

2-methyl-3-oxopropanoateReach from here →

Catalysed by CYP2E1, AGXT2cytosol

L-methionineReach from here →

Catalysed by CYP2E1, TYW1B, TYW1cytosol

glutathioneReach from here →

Catalysed by CYP2E1, GLO1, GLOD4, HAGHcytosol

L-alanineReach from here →

Catalysed by CYP2E1, AGXT2cytosol, mitochondrial matrixOne of 18 routes

1-hexadecanoylglycerone 3-phosphateReach from here →

Catalysed by CYP2E1, TPI1, GNPATcytosol