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a 1-acylglycerone 3-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

14 compounds within 3 steps: 2 in 1, 3 in 2, 9 in 3

Does it reach a compound?

One step

a long-chain fatty acidReach from here →
1. a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
Catalysed by AGPS
a 1-O-alkylglycerone 3-phosphateReach from here →
1. a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
Catalysed by AGPS

Two steps

a 1-O-alkyl-sn-glycero-3-phosphateReach from here →
1. a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
2. a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) = a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)
Catalysed by AGPS, DHRS7B
hexadecanoateReach from here →
1. a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
2. 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
Catalysed by AGPS
a long-chain fatty acyl-CoAReach from here →

Three steps

hexadecanalReach from here →
Catalysed by AGPS, ALDH3B1, ALDH3B2, ALDH3A2
all-trans-retinyl hexadecanoateReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate

Catalysed by AGPS, SLC27A2, ACSL4, ACSL3 and 10 more

Catalysed by AGPS, RPE65

S-hexadecanoyl-N-acetylcysteamineReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)

Catalysed by AGPS, PPT1, PPT2

S-hexadecanoyl-N-acetylcysteine methyl esterReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
S-hexadecanoyl-N-acetylcysteine methyl ester + H2O = N-acetylcysteine methyl ester + hexadecanoate + H(+)

Catalysed by AGPS, PPT1

16-hydroxyhexadecanoateReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 16-hydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by AGPS, CYP4A11, CYP4V2, CYP4F11

hexadecanoyl-CoAReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate

Catalysed by AGPS, SLC27A2, ACSL4, ACSL3 and 8 more

N-hexadecanoylsphing-4-enineReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate

Catalysed by AGPS, NAAA, ASAH1, ACER2 and 1 more

(R)-2-hydroxyhexadecanoateReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (R)-2-hydroxyhexadecanoate + 2 Fe(III)-[cytochrome b5] + H2O

Catalysed by AGPS, FA2H

a 1-O-alkyl-sn-glycero-3-phosphoethanolamineReach from here →

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)
a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) = a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)
a 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)

Catalysed by AGPS, DHRS7B, ENPP2