Compound

dihydroxyacetone phosphate

An important intermediate in lipid biosynthesis and in glycolysis.

Definition from MeSH (D004099), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:57642ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of dihydroxyacetone phosphate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C3H5O6P
Mass: 168.041 g/mol
Charge: -2
InChIKey: GNGACRATGGDKBX-UHFFFAOYSA-L
SMILES: O=C(CO)COP(=O)([O-])[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Chemical structure

dihydroxyacetone phosphate has the functional parent dihydroxyacetoneCompoundChEBI CHEBI:57642Inferred only

Statements

28 statements

28 statements · 1 reference database · Subject: dihydroxyacetone phosphate · Sources: Rhea

Order

dihydroxyacetone phosphate is converted to D-glyceraldehyde 3-phosphateCompoundRhea RHEA:18585Inferred only
D-glyceraldehyde 3-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:18585Inferred only
dihydroxyacetone is converted to dihydroxyacetone phosphateCompoundRhea RHEA:51728Inferred only
dihydroxyacetone phosphate is converted to dihydroxyacetoneCompoundRhea RHEA:15773Inferred only
dihydroxyacetone is converted to dihydroxyacetone phosphateCompoundRhea RHEA:15773Inferred only
dihydroxyacetone phosphate is converted to dihydroxyacetoneCompoundRhea RHEA:51728Inferred only
dihydroxyacetone phosphate is converted to methylglyoxalCompoundRhea RHEA:17937Inferred only
methylglyoxal is converted to dihydroxyacetone phosphateCompoundRhea RHEA:17937Inferred only
dihydroxyacetone phosphate is converted to sn-glycerol 1-phosphateCompoundRhea RHEA:21416Inferred only
dihydroxyacetone phosphate is converted to sn-glycerol 1-phosphateCompoundRhea RHEA:21412Inferred only
sn-glycerol 1-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:21412Inferred only
sn-glycerol 1-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:21416Inferred only

Show the remaining 16

sn-glycerol 3-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:11096Inferred only
dihydroxyacetone phosphate is converted to sn-glycerol 3-phosphateCompoundRhea RHEA:31283Inferred only
sn-glycerol 3-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:18369Inferred only
dihydroxyacetone phosphate is converted to sn-glycerol 3-phosphateCompoundRhea RHEA:18369Inferred only
sn-glycerol 3-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:31283Inferred only
dihydroxyacetone phosphate is converted to sn-glycerol 3-phosphateCompoundRhea RHEA:11096Inferred only
sn-glycerol 3-phosphate is converted to dihydroxyacetone phosphateCompoundRhea RHEA:11092Inferred only
dihydroxyacetone phosphate is a substrate of ALDOAProteinRhea RHEA:14729Inferred only
dihydroxyacetone phosphate is a substrate of ALDOBProteinRhea RHEA:30851Inferred only
dihydroxyacetone phosphate is a substrate of ALDOBProteinRhea RHEA:14729Inferred only
dihydroxyacetone phosphate is a substrate of ALDOCProteinRhea RHEA:14729Inferred only
dihydroxyacetone phosphate is a substrate of GNPATProteinRhea RHEA:17657Inferred only
dihydroxyacetone phosphate is a substrate of GNPATProteinRhea RHEA:40715Inferred only
dihydroxyacetone phosphate is a substrate of TKFCProteinRhea RHEA:15773Inferred only
dihydroxyacetone phosphate is a substrate of TPI1ProteinRhea RHEA:17937Inferred only
dihydroxyacetone phosphate is a substrate of TPI1ProteinRhea RHEA:18585Inferred only

Reactions

45 reactions

sn-glycerol 3-phosphate+NAD(1-)dihydroxyacetone phosphate+NADH(2-)+hydron
Catalysed by GPD1 or GPD1L
Reaction pageLeft to rightBalanced
Rhea RHEA:11092CC BY 4.0Reference data
sn-glycerol 3-phosphate+NADP(3-)dihydroxyacetone phosphate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:11096CC BY 4.0Reference data
CHEBI:57846CHEBI:18041+dihydroxyacetone phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:12933CC BY 4.0Reference data
CHEBI:579493-oxopropanoate+dihydroxyacetone phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:13177CC BY 4.0Reference data
beta-D-fructose 1,6-bisphosphateD-glyceraldehyde 3-phosphate+dihydroxyacetone phosphate
Catalysed by ALDOA or ALDOB or ALDOC
Reaction pageReversibleBalanced
Rhea RHEA:14729CC BY 4.0Reference data
dihydroxyacetone+ATP(4-)dihydroxyacetone phosphate+ADP(3-)+hydron
Catalysed by TKFC
Reaction pageDirection not assertedBalanced
Rhea RHEA:15773CC BY 4.0Reference data
dihydroxyacetone phosphate+an acyl-CoAa 1-acylglycerone 3-phosphate+coenzyme A(4-)
Catalysed by GNPAT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17657CC BY 4.0Reference data
dihydroxyacetone phosphatemethylglyoxal+hydrogenphosphate
Catalysed by TPI1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17937CC BY 4.0Reference data
sn-glycerol 3-phosphate+dioxygendihydroxyacetone phosphate+hydrogen peroxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:18369CC BY 4.0Reference data
dihydroxyacetone+phosphoenolpyruvatedihydroxyacetone phosphate+pyruvate
Reaction pageDirection not assertedBalanced
Rhea RHEA:18381CC BY 4.0Reference data
D-glyceraldehyde 3-phosphatedihydroxyacetone phosphate
Catalysed by TPI1
Reaction pageReversibleBalanced
Rhea RHEA:18585CC BY 4.0Reference data
a quinone+sn-glycerol 3-phosphatedihydroxyacetone phosphate+a quinol
Catalysed by GPD2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18977CC BY 4.0Reference data

Show the remaining 33

Other names

4 names

Resolves to: dihydroxyacetone phosphate

Also called: dihydroxyacetone phosphate dianionglycerone phosphateglycerone phosphate dianion
Systematic name: 3-hydroxy-2-oxopropyl phosphate