What it touches on the way
Mechanistic reach
15 entities
15 entities reached.
0 reported hops15 assembled from the scaffold
- ALDH2ProteinUNIPROT:P05091metabolized byInferred only64 paths32 endpoints
- ALDH1B1ProteinUNIPROT:P30837metabolized byInferred only22 paths11 endpoints
- ADH1AProteinUNIPROT:P07327metabolized byInferred only17 paths17 endpoints
- ADH4ProteinUNIPROT:P08319metabolized byInferred only14 paths14 endpoints
- ALDH3A2ProteinUNIPROT:P51648metabolized byInferred only14 paths14 endpoints
- ALDH7A1ProteinUNIPROT:P49419metabolized byInferred only13 paths13 endpoints
- ADH7ProteinUNIPROT:P40394metabolized byInferred only12 paths12 endpoints
- ADH1CProteinUNIPROT:P00326metabolized byInferred only11 paths11 endpoints
- ADH5ProteinUNIPROT:P11766metabolized byInferred only10 paths10 endpoints
- ALDH18A1ProteinUNIPROT:P54886metabolized byInferred only10 paths10 endpoints
- ALDH4A1ProteinUNIPROT:P30038metabolized byInferred only9 paths9 endpoints
- ALDH9A1ProteinUNIPROT:P49189metabolized byInferred only7 paths7 endpoints
What the reference databases state
Statements
22 statements
22 statements · 1 reference database · Subject: (R)-lactaldehyde · Sources: Human-GEM
- (R)-lactaldehyde is converted to (R)-lactic acidCompoundHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is converted to (R)-lactic acidCompoundHuman-GEM MAR08504Inferred only
- methylglyoxal is converted to (R)-lactaldehydeCompoundHuman-GEM MAR03856Inferred only
- methylglyoxal is converted to (R)-lactaldehydeCompoundHuman-GEM MAR08501Inferred only
- (R)-lactaldehyde is metabolised by ADH1AProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ADH1CProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ADH4ProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ADH5ProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ADH6ProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ADH7ProteinHuman-GEM MAR08502Inferred only
- (R)-lactaldehyde is metabolised by ALDH18A1ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH1B1ProteinHuman-GEM MAR08504Inferred only
Show the remaining 10
- (R)-lactaldehyde is metabolised by ALDH1B1ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH2ProteinHuman-GEM MAR08504Inferred only
- (R)-lactaldehyde is metabolised by ALDH2ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH3A2ProteinHuman-GEM MAR08504Inferred only
- (R)-lactaldehyde is metabolised by ALDH4A1ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH5A1ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH6A1ProteinHuman-GEM MAR01474Inferred only
- (R)-lactaldehyde is metabolised by ALDH7A1ProteinHuman-GEM MAR08504Inferred only
- (R)-lactaldehyde is metabolised by ALDH9A1ProteinHuman-GEM MAR08504Inferred only
- (R)-lactaldehyde is a substrate of ADHFE1ProteinHuman-GEM MAR08502Inferred only
Reactions
11 reactions
(R)-lactaldehyde+water+NAD(+)(R)-lactic acid+2proton+NADH(2-)
Catalysed by ALDH18A1 or ALDH2 or ALDH5A1 or ALDH6A1 or ALDH1B1 or ALDH4A1
Reaction pageLeft to rightBalancedEC 1.2.1.3GO:0005759
Human-GEM MAR01474CC BY 4.0Reference data
proton+methylglyoxal+NADH(2-)(R)-lactaldehyde+NAD(+)
Reaction pageLeft to rightBalancedEC 1.1.1.79, 1.1.1.81GO:0005829
Human-GEM MAR03856CC BY 4.0Reference data
proton+methylglyoxal+NADPH(4-)(R)-lactaldehyde+NADP(3-)
Catalysed by GRHPR
Reaction pageLeft to rightBalancedEC 1.1.1.79, 1.1.1.81GO:0005829
Human-GEM MAR08501CC BY 4.0Reference data
(R)-S-lactoylglutathione+proton+NADH(2-)(R)-lactaldehyde+CHEBI:16856+NAD(+)
Catalysed by ADHFE1 or ADH6 or ADH1A or ADH7 or ADH5 or ADH4 or ADH1C
Reaction pageReversibleBalancedEC 1.1.1.1GO:0005829
Human-GEM MAR08502CC BY 4.0Reference data
(R)-lactaldehyde+water+NAD(+)(R)-lactic acid+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3GO:0005829
Human-GEM MAR08504CC BY 4.0Reference data
NAD(+)+propane-1,2-diol(R)-lactaldehyde+proton+NADH(2-)
Catalysed by ADHFE1 or ADH6 or PTGR3 or ADH1A or ADH7 or ADH5 or ADH4 or ADH1C
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR08507CC BY 4.0Reference data
(R)-lactaldehyde+proton+NADPH(4-)NADP(3-)+propane-1,2-diol
Catalysed by AKR7A2 or AKR1B1 or AKR1A1
Reaction pageLeft to rightBalancedEC 1.1.1.21, 1.1.1.2GO:0005829
Human-GEM MAR08509CC BY 4.0Reference data
CHEBI:28972+NAD(1-)(R)-lactaldehyde+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23872CC BY 4.0Reference data
(R)-lactaldehyde+NAD(1-)methylglyoxal+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24528CC BY 4.0Reference data
(R)-lactaldehyde+3-hydroxypyruvateCHEBI:231436
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:80063CC BY 4.0Reference data
(R)-lactaldehyde+3-hydroxypyruvateCHEBI:231437
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:80067CC BY 4.0Reference data