hydrogen sulfide

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by TSTD1, GPX1, GPX2, GPX4

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (R)-S-lactoylglutathione = methylglyoxal + glutathione

Catalysed by TSTD1, GLO1

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. S-formylglutathione + H2O = formate + glutathione + H(+)

Catalysed by TSTD1, ESD

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of cysteine and methionine (cytosol to extracellular)

Catalysed by CBS, SLC7A5cytosol, extracellular spaceOne of 6 routes

1. hydrogen sulfide + 2 O2 = sulfate + H(+)
2. N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate

Catalysed by SOD1, SGSH

1. hydrogen sulfide + 2 O2 = sulfate + H(+)
2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)

Catalysed by SOD1, STS

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of cysteine and tryptophan (cytosol to extracellular)

Catalysed by CBS, SLC7A5cytosol, extracellular spaceOne of 4 routes

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of alanine and cysteine (cytosol to extracellular)

Catalysed by CBS, SLC7A5cytosol, extracellular spaceOne of 14 routes

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. leukotriene C4 = leukotriene A4 + glutathione

Catalysed by TSTD1, MGST3, GSTM4, LTC4S and 1 more

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of asparagine and cysteine (cytosol to extracellular)

Catalysed by CBS, SLC7A5cytosol, extracellular spaceOne of 4 routes

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of cysteine and phenylalanine (cytosol to extracellular)

Catalysed by CBS, SLC7A5cytosol, extracellular spaceOne of 6 routes

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. L-glutamate:L-cysteine gamma-ligase (ADP-forming)

Catalysed by CBS, GCLC, GCLMcytosolOne of 2 routes

1. hydrogen sulfide + 2 O2 = sulfate + H(+)
2. ATP:sulfate adenylyltransferase

Catalysed by SOD1, PAPSS1, PAPSS2cytosolOne of 4 routes

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)

Catalysed by TSTD1One of 23 routes

1. a quinone + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + a quinol
2. trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)

Catalysed by SQOR, PRODH2

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. glutathione = L-cysteinylglycine + 5-oxo-L-proline

Catalysed by TSTD1, CHAC2, CHAC1

1. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)
2. 2-oxo-3-sulfanylpropanoate + L-kynurenine = kynurenate + L-cysteine + H2O

Catalysed by MPST, AADAT

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. 2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine

Catalysed by CBS, CARS2cytosol

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. (R)-4'-phosphopantothenate:L-cysteine ligase

Catalysed by CBS, PPCScytosolOne of 4 routes

1. a quinone + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + a quinol
2. L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)

Catalysed by SQOR, PRODH, PRODH2

1. hydrogen sulfide + 2 O2 = sulfate + H(+)
2. estrone 3-sulfate + H2O = estrone + sulfate + H(+)

Catalysed by SOD1, STS

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. L-Cysteine:oxygen oxidoreductase

Catalysed by CBS, CDO1cytosolOne of 2 routes

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. glutathione + H2O = L-cysteinylglycine + L-glutamate

Catalysed by TSTD1, GGT3P, GGT1, GGT5 and 2 moreOne of 2 routes

1. hydrogen sulfide + 2 O2 = sulfate + H(+)
2. Transport of 5-Hydroxyindoleacetate

Catalysed by SOD1, SLC4A1extracellular space, cytosolOne of 2 routes

1. ubiquinone-10 + hydrogen sulfide + sulfite + 2 H(+) = ubiquinol-10 + thiosulfate
2. 3-demethylubiquinol-10 + S-adenosyl-L-methionine = ubiquinol-10 + S-adenosyl-L-homocysteine + H(+)

Catalysed by SQOR, COQ3

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O

Catalysed by TSTD1, GPX1, GPX4

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by CBS, MOCOScytosol

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)

Catalysed by TSTD1, ABCC4inner side of the membrane, outer side of the membrane

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by TSTD1, GPX1, GPX2, GPX4

1. L-cysteinyl-[sulfatase] + 2 a thiol + O2 = an organic disulfide + 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + H2O + H(+)
2. a thiol + S-adenosyl-L-methionine = a methyl thioether + S-adenosyl-L-homocysteine + H(+)

Catalysed by SUMF1, TMT1B, TMT1A

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by TSTD1, PTGES, MGST3, GPX1 and 3 more

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Catalysed by TSTD1, GPX1, GPX4

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)

Catalysed by TSTD1, GSTT4, GSTA4, GSTZ1 and 20 moreOne of 2 routes

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O

Catalysed by TSTD1, GPX1, GSTA1, GPX2 and 1 more

1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
2. taurochenodeoxycholate(in) + glutathione(in) + ATP + H2O = taurochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)

Catalysed by TSTD1, ABCC4inner side of the membrane, outer side of the membrane

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. transport of cysteine and tryptophan (cytosol to extracellular)
3. beta-carboline hydrolysis

Catalysed by CBS, SLC7A5cytosol, extracellular space

1. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
2. N-acetylglutamate synthase (N-acetyl-L-cysteine)
3. Carnitine O-Palmitoyltransferase

Catalysed by CBS, NAGS and 1 more