Compound

5-oxo-L-proline

Conjugate base of 5-oxo-L-proline.

Definition from ChEBI (CHEBI:58402), read 2026-09-23. CC BY 4.0.

CHEBI:58402ChEBI

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Structure

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A generated conformer of 5-oxo-L-proline — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C5H6NO3
Mass: 128.107 g/mol
Charge: -1
InChIKey: ODHCTXKNWHHXJC-VKHMYHEASA-M
SMILES: O=C1CC[C@@H](C(=O)[O-])N1
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 1 reference database · Subject: 5-oxo-L-proline · Sources: Rhea

Order

5-oxo-L-proline is a substrate of CHAC1ProteinRhea RHEA:47724Inferred only
5-oxo-L-proline is a substrate of CHAC2ProteinRhea RHEA:47724Inferred only
5-oxo-L-proline is a substrate of GGACTProteinRhea RHEA:16961Inferred only
5-oxo-L-proline is a substrate of OPLAHProteinRhea RHEA:10348Inferred only
5-oxo-L-proline is transported by SLC5A8ProteinRhea RHEA:72971Inferred only

Reactions

6 reactions

5-oxo-L-proline+ATP(4-)+2waterL-glutamate(1-)+ADP(3-)+hydrogenphosphate+hydron
Catalysed by OPLAH
Reaction pageDirection not assertedBalanced
Rhea RHEA:10348CC BY 4.0Reference data
epsilon-(gamma-L-glutamyl)-L-lysine5-oxo-L-proline+L-lysine
Catalysed by GGACT
Reaction pageDirection not assertedBalanced
Rhea RHEA:16961CC BY 4.0Reference data
an alpha-(gamma-L-glutamyl)-L-amino acid5-oxo-L-proline+an L-alpha-amino acid
Catalysed by GGCT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20505CC BY 4.0Reference data
CHEBI:65086CHEBI:65085+5-oxo-L-proline
Reaction pageDirection not assertedBalanced
Rhea RHEA:33995CC BY 4.0Reference data
glutathioneL-cysteinylglycine+5-oxo-L-proline
Catalysed by CHAC2 or CHAC1
Reaction pageDirection not assertedBalanced
Rhea RHEA:47724CC BY 4.0Reference data
5-oxo-L-proline+2sodium(1+)5-oxo-L-proline+2sodium(1+)
Transported by SLC5A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:72971CC BY 4.0Reference data

Other names

2 names

Resolves to: 5-oxo-L-proline

Systematic name: (2S)-5-oxopyrrolidine-2-carboxylate5-oxo-L-prolate