Compound
(5-hydroxyindol-3-yl)acetate
The indol-3-yl carboxylic acid anion formed by loss of a proton from the carboxy group of (5-hydroxyindol-3-yl)acetic acid; principal microspecies at pH 7.3
Definition from ChEBI (CHEBI:62622), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H8NO3
- Mass
- 190.178 g/mol
- Charge
- -1
- InChIKey
- DUUGKQCEGZLZNO-UHFFFAOYSA-M
- SMILES
- O=C([O-])Cc1cnc2ccc(O)cc12
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
8 statements
8 statements · 2 reference databases · Subject: (5-hydroxyindol-3-yl)acetate · Sources: Human-GEM, Rhea
- (5-hydroxyindol-3-yl)acetaldehyde is converted to (5-hydroxyindol-3-yl)acetateCompoundHuman-GEM MAR00051Inferred only
- (5-hydroxyindol-3-yl)acetaldehyde is converted to (5-hydroxyindol-3-yl)acetateCompoundHuman-GEM MAR04559Inferred only
- (5-hydroxyindol-3-yl)acetaldehyde is converted to (5-hydroxyindol-3-yl)acetateCompoundHuman-GEM MAR04560Inferred only
- (5-hydroxyindol-3-yl)acetate is converted to (5-hydroxyindol-3-yl)acetaldehydeCompoundRhea RHEA:31215Inferred only
- (5-hydroxyindol-3-yl)acetaldehyde is converted to (5-hydroxyindol-3-yl)acetateCompoundRhea RHEA:31215Inferred only
- (5-hydroxyindol-3-yl)acetate is metabolised by ALDH9A1ProteinRhea RHEA:31215Inferred only
- (5-hydroxyindol-3-yl)acetate is a substrate of ASMTProteinHuman-GEM MAR04564Inferred only
- (5-hydroxyindol-3-yl)acetate is transported by SLC4A1ProteinHuman-GEM MAR09059Inferred only
Reactions
7 reactions
(5-hydroxyindol-3-yl)acetaldehyde+water+NAD(+)(5-hydroxyindol-3-yl)acetate+2proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.2.1.88GO:0005759
Human-GEM MAR00051CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetaldehyde+water+NAD(+)(5-hydroxyindol-3-yl)acetate+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3GO:0005829
Human-GEM MAR04559CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetaldehyde+water+dioxygen(5-hydroxyindol-3-yl)acetate+proton+hydrogen peroxide
Catalysed by AOX1
Reaction pageLeft to rightBalancedEC 1.2.3.1GO:0005829
Human-GEM MAR04560CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetate+S-adenosyl-L-methionineMAM01112c+proton+CHEBI:16680
Catalysed by ASMT
Reaction pageLeft to rightBalancedEC 2.1.1.4GO:0005829
Human-GEM MAR04564CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetate+sulfate(5-hydroxyindol-3-yl)acetate+sulfate
Transported by SLC4A1
Reaction pageReversibleBalancedGO:0005615, GO:0005829
Human-GEM MAR09059CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09843CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetaldehyde+NAD(1-)+water(5-hydroxyindol-3-yl)acetate+NADH(2-)+2hydron
Catalysed by ALDH9A1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:31215CC BY 4.0Reference data
Where it reaches
2 systems, 2 regions, 4 tissues, 4 transporter routes — routes, not measurements: transporters known to carry (5-hydroxyindol-3-yl)acetate are expressed there, and no source reports it arriving.
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Other names
6 names
Resolves to: (5-hydroxyindol-3-yl)acetate
- Also called
- (5-hydroxyindol-3-yl)acetate(1-)(5-hydroxyindol-3-yl)acetate(1−)5-hydroxy-3-indole acetic acid anion5-hydroxyindoleacetate(1-)5-hydroxyindoleacetate(1−)
- Systematic name
- (5-hydroxy-1H-indol-3-yl)acetate