Compound
an S-substituted glutathione
A peptide anion obtained by deprotonation of the carboxy groups and concomitant protonation of the amino group of any S-substituted glutathione. Major structure at pH 7.3
Definition from ChEBI (CHEBI:90779), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C10H15N3O6SR
- Mass
- 305.309 g/mol
- Charge
- -1
- SMILES
- *SC[C@H](NC(=O)CC[C@H]([NH3+])C(=O)[O-])C(=O)NCC(=O)[O-]
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
11 entities
11 entities reached.
0 reported hops11 assembled from the scaffold
- RALBP1ProteinUNIPROT:Q15311transported byInferred only35 paths35 endpoints
- GGT1ProteinUNIPROT:P19440substrate ofInferred only34 paths34 endpoints
- ABCC3ProteinUNIPROT:O15438transported byInferred only33 paths30 endpoints
- GGT5ProteinUNIPROT:P36269substrate ofInferred only23 paths23 endpoints
- ABCC2ProteinUNIPROT:Q92887transported byInferred only15 paths15 endpoints
- ABCC4ProteinUNIPROT:O15439transported byInferred only10 paths10 endpoints
- GGT6ProteinUNIPROT:Q6P531substrate ofInferred only9 paths9 endpoints
- GGT7ProteinUNIPROT:Q9UJ14substrate ofInferred only9 paths9 endpoints
- GGT3PProteinUNIPROT:A6NGU5substrate ofInferred only8 paths8 endpoints
- ABCC1ProteinUNIPROT:P33527transported byInferred only2 paths2 endpoints
- ABCC6ProteinUNIPROT:O95255transported byInferred only2 paths2 endpoints
What the reference databases state
Chemical structure
- an S-substituted glutathione has the functional parent glutathioneCompoundChEBI CHEBI:90779Inferred only
Statements
14 statements
14 statements · 1 reference database · Subject: an S-substituted glutathione · Sources: Rhea
- an S-substituted glutathione is converted to an S-substituted L-cysteinylglycineCompoundRhea RHEA:59468Inferred only
- an S-substituted glutathione is a substrate of GGT1ProteinRhea RHEA:59468Inferred only
- an S-substituted glutathione is a substrate of GGT3PProteinRhea RHEA:59468Inferred only
- an S-substituted glutathione is a substrate of GGT5ProteinRhea RHEA:59468Inferred only
- an S-substituted glutathione is a substrate of GGT6ProteinRhea RHEA:59468Inferred only
- an S-substituted glutathione is a substrate of GGT7ProteinRhea RHEA:59468Inferred only
- an S-substituted glutathione is transported by ABCC1ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by ABCC10ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by ABCC11ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by ABCC2ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by ABCC3ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by ABCC4ProteinRhea RHEA:19121Inferred only
Show the remaining 2
- an S-substituted glutathione is transported by ABCC6ProteinRhea RHEA:19121Inferred only
- an S-substituted glutathione is transported by RALBP1ProteinRhea RHEA:19121Inferred only
Reactions
5 reactions
RX+glutathionean S-substituted glutathione+a halide anion+hydron
Catalysed by GSTT4 or GSTA4 or GSTZ1 or LANCL1 or HPGDS or GSTA1 or GSTA2 or GSTP1 or GSTM1 or GSTT2 or GSTT2B or MGST1 and 11 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:16437CC BY 4.0Reference data
an S-substituted glutathione+ATP(4-)+wateran S-substituted glutathione+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC3 or ABCC4 or ABCC6 or ABCC1 or RALBP1 or ABCC10 or ABCC2 or ABCC11
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19121CC BY 4.0Reference data
apo-[alkylcobalamin reductase]+an R-cob(III)alamin+glutathionecob(I)alamin-[alkylcobalamin reductase]+an S-substituted glutathione+hydron
Catalysed by MMACHC
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:40719CC BY 4.0Reference data
an S-substituted glutathione+wateran S-substituted L-cysteinylglycine+L-glutamate(1-)
Catalysed by GGT3P or GGT1 or GGT5 or GGT6 or GGT7
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:59468CC BY 4.0Reference data
an S-substituted glutathione+waterCHEBI:143789+glycine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:60448CC BY 4.0Reference data
Where it reaches
9 systems, 21 regions, 64 tissues, 79 transporter routes — routes, not measurements: transporters known to carry an S-substituted glutathione are expressed there, and no source reports it arriving.
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