Compound
3-sulfino-L-alanine
An α-amino-acid anion that is the conjugate base of 3-sulfino-L-alanine, arising from deprotonation of the sulfino and carboxy groups and protonation of the amino group; major species at pH 7.3.
Definition from ChEBI (CHEBI:61085), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C3H6NO4S
- Mass
- 152.151 g/mol
- Charge
- -1
- InChIKey
- ADVPTQAUNPRNPO-REOHCLBHSA-M
- SMILES
- [NH3+][C@@H](CS(=O)[O-])C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- SLC25A12ProteinUNIPROT:O75746transported byInferred only268 paths66 endpoints
- SLC25A13ProteinUNIPROT:Q9UJS0transported byInferred only104 paths25 endpoints
- GOT2ProteinUNIPROT:P00505substrate ofInferred only34 paths34 endpoints
- GAD1ProteinUNIPROT:Q99259substrate ofInferred only28 paths28 endpoints
- GOT1ProteinUNIPROT:P17174substrate ofInferred only24 paths24 endpoints
- CSADProteinUNIPROT:Q9Y600substrate ofInferred only16 paths8 endpoints
- GADL1ProteinUNIPROT:Q6ZQY3substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
22 statements
22 statements · 2 reference databases · Subject: 3-sulfino-L-alanine · Sources: Human-GEM, Rhea
- 3-sulfino-L-alanine is converted to 3-sulfinopyruvateCompoundHuman-GEM MAR03865Inferred only
- 3-sulfinopyruvate is converted to 3-sulfino-L-alanineCompoundRhea RHEA:70295Inferred only
- 3-sulfino-L-alanine is converted to 3-sulfinopyruvateCompoundHuman-GEM MAR03861Inferred only
- 3-sulfino-L-alanine is converted to CHEBI:16668CompoundHuman-GEM MAR03910Inferred only
- 3-sulfino-L-alanine is converted to hypotaurineCompoundRhea RHEA:16877Inferred only
- hypotaurine is converted to 3-sulfino-L-alanineCompoundRhea RHEA:16877Inferred only
- L-cysteine is converted to 3-sulfino-L-alanineCompoundHuman-GEM MAR03908Inferred only
- L-cysteine is converted to 3-sulfino-L-alanineCompoundRhea RHEA:20441Inferred only
- 3-sulfino-L-alanine is a substrate of CSADProteinRhea RHEA:16877Inferred only
- 3-sulfino-L-alanine is a substrate of CSADProteinHuman-GEM MAR03910Inferred only
- 3-sulfino-L-alanine is a substrate of GAD1ProteinHuman-GEM MAR03910Inferred only
- 3-sulfino-L-alanine is a substrate of GADL1ProteinRhea RHEA:16877Inferred only
Show the remaining 10
- 3-sulfino-L-alanine is a substrate of GOT1ProteinHuman-GEM MAR03861Inferred only
- 3-sulfino-L-alanine is a substrate of GOT2ProteinHuman-GEM MAR03865Inferred only
- 3-sulfino-L-alanine is transported by SLC25A12ProteinHuman-GEM MAR03863Inferred only
- 3-sulfino-L-alanine is transported by SLC25A12ProteinHuman-GEM MAR03864Inferred only
- 3-sulfino-L-alanine is transported by SLC25A12ProteinRhea RHEA:70975Inferred only
- 3-sulfino-L-alanine is transported by SLC25A12ProteinRhea RHEA:70967Inferred only
- 3-sulfino-L-alanine is transported by SLC25A13ProteinRhea RHEA:70967Inferred only
- 3-sulfino-L-alanine is transported by SLC25A13ProteinRhea RHEA:70975Inferred only
- 3-sulfino-L-alanine is transported by SLC25A13ProteinHuman-GEM MAR03863Inferred only
- 3-sulfino-L-alanine is transported by SLC25A13ProteinHuman-GEM MAR03864Inferred only
Reactions
14 reactions
3-sulfino-L-alanine+2-oxoglutarate(2-)+proton3-sulfinopyruvate+L-glutamate(1-)
Catalysed by GOT1
Reaction pageLeft to rightBalancedEC 2.6.1.1cytosol
Human-GEM MAR03861CC BY 4.0Reference data
3-sulfino-L-alanine+L-aspartate3-sulfino-L-alanine+L-aspartate
Transported by SLC25A13 or SLC25A12
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR03863CC BY 4.0Reference data
3-sulfino-L-alanine+L-glutamate(1-)+proton3-sulfino-L-alanine+L-glutamate(1-)+proton
Transported by SLC25A13 or SLC25A12
Reaction pageLeft to rightBalancedmitochondrial matrix, cytosol, mitochondrial intermembrane space
Human-GEM MAR03864CC BY 4.0Reference data
3-sulfino-L-alanine+2-oxoglutarate(2-)+proton3-sulfinopyruvate+L-glutamate(1-)
Catalysed by GOT2
Reaction pageLeft to rightBalancedEC 2.6.1.1, 2.6.1.7mitochondrial matrix
Human-GEM MAR03865CC BY 4.0Reference data
L-cysteine+dioxygen3-sulfino-L-alanine+2proton
Catalysed by CDO1
Reaction pageLeft to rightBalancedEC 1.13.11.20cytosol
Human-GEM MAR03908CC BY 4.0Reference data
3-sulfino-L-alanine+2protoncarbon dioxide+CHEBI:16668
Reaction pageLeft to rightBalancedEC 4.1.1.15, 4.1.1.29cytosol
Human-GEM MAR03910CC BY 4.0Reference data
23-sulfino-L-alanine+2proton+dioxygen2MAM02350c
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR08063CC BY 4.0Reference data
23-sulfino-L-alanine+2proton+dioxygen2MAM02350m
Reaction pageLeft to rightBalancedmitochondrial matrix
Human-GEM MAR08064CC BY 4.0Reference data
3-sulfino-L-alanine+hydronhypotaurine+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:16877CC BY 4.0Reference data
L-cysteine+dioxygen3-sulfino-L-alanine+hydron
Catalysed by CDO1
Reaction pageLeft to rightBalanced
Rhea RHEA:20441CC BY 4.0Reference data
3-sulfino-L-alanine+watersulfite+L-alanine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:28278CC BY 4.0Reference data
3-sulfino-L-alanine+2-oxoglutarate(2-)3-sulfinopyruvate+L-glutamate(1-)
Catalysed by GOT1
Reaction pageRight to leftBalanced
Rhea RHEA:70295CC BY 4.0Reference data
Where it reaches
10 systems, 22 regions, 68 tissues, 89 transporter routes — routes, not measurements: transporters known to carry 3-sulfino-L-alanine are expressed there, and no source reports it arriving.
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Other names
7 names
Resolves to: 3-sulfino-L-alanine
- Also called
- (2R)-2-ammonio-3-sulfinatopropanoatecysteine sulfinatecysteine sulfinic acid(1-)cysteine sulfinic acid(1−)cysteinesulfinateL-cysteine sulfinate
- Systematic name
- (2R)-2-azaniumyl-3-sulfinatopropanoate