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Reference

Evidence

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Reach

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A reference for what the literature reports. Not medical advice.

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hypothiocyanous acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

11 compounds within 3 steps: 1 in 1, 2 in 2, 8 in 3

Does it reach a compound?

One step

thiocyanateReach from here →
1. Dihydrolipoyl Dehydrogenase
Catalysed by LPOextracellular spaceOne of 3 routes

Two steps

hydrogen cyanideReach from here →
1. Dihydrolipoyl Dehydrogenase
2. thiosulfate:cyanide sulfurtranserase
Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrixOne of 2 routes
thiosulfateReach from here →
1. Dihydrolipoyl Dehydrogenase
2. thiosulfate:cyanide sulfurtranserase
Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrixOne of 2 routes

Three steps

pyruvateReach from here →
Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrix, cytosol
(S)-malateReach from here →
Catalysed by LPO,

extracellular space, mitochondrial matrix, cytosol

One of 2 routes

sulfateReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)

Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrix, cytosolOne of 3 routes

sulfiteReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
thiosulfate:cyanide sulfurtranserase

Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrixOne of 6 routes

fumaric acidReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
transport of fumarate and thiosulfate (cytosol to mitochondria)

Catalysed by LPO, MPST, TST, SLC25A10extracellular space, mitochondrial matrix, cytosolOne of 2 routes

hydrogen sulfideReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)

Catalysed by LPO, MPST, TSTextracellular space, mitochondrial matrix, cytosolOne of 2 routes

glutathione disulfideReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)

Catalysed by LPO, MPST, TST, TSTD1extracellular space, mitochondrial matrix

S-sulfanylglutathioneReach from here →

Dihydrolipoyl Dehydrogenase
thiosulfate:cyanide sulfurtranserase
thiosulfate + glutathione = S-sulfanylglutathione + sulfite + H(+)

Catalysed by LPO, MPST, TST, TSTD1extracellular space, mitochondrial matrix