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3-demethylubiquinol-10

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

8 compounds within 3 steps: 3 in 1, 2 in 2, 3 in 3

Does it reach a compound?

One step

ubiquinolReach from here →
1. coenzyme Q3, methyltransferase (3-demethylubiquinol-10)
Catalysed by COQ3mitochondrial matrix
3-demethylubiquinone-10Reach from here →
1. 3-demethylubiquinone-10 + NADH + 2 H(+) = 3-demethylubiquinol-10 + NAD(+)
Catalysed by RTN4IP1One of 2 routes
ubiquinol-10Reach from here →
1. 3-demethylubiquinol-10 + S-adenosyl-L-methionine = ubiquinol-10 + S-adenosyl-L-homocysteine + H(+)
Catalysed by COQ3

Two steps

ubiquinonesReach from here →
1. coenzyme Q3, methyltransferase (3-demethylubiquinol-10)
2. succinate:quinone oxidoreductase
Catalysed by COQ3, SDHD, SDHB, SDHA and 1 moremitochondrial matrixOne of 5 routes
ferrocytochrome cReach from here →
1. coenzyme Q3, methyltransferase (3-demethylubiquinol-10)
2. ubiquinol:ferricytochrome-c oxidoreductase
Catalysed by COQ3, UQCRQ, UQCR11, MT-CYB and 7 more

Three steps

ferricytochrome cReach from here →
Catalysed by COQ3, UQCRQ, UQCR11, MT-CYB and 7 moremitochondrial matrix, mitochondrial intermembrane space, cytosolOne of 4 routes
fumaric acidReach from here →

mitochondrial matrix, mitochondrial intermembrane space

Catalysed by COQ3, SDHD, SDHB, SDHA and 1 moremitochondrial matrix

(13S)-hydroperoxy-(9Z,11E)-octadecadienoateReach from here →

coenzyme Q3, methyltransferase (3-demethylubiquinol-10)
ubiquinol:ferricytochrome-c oxidoreductase
13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion

Catalysed by COQ3, UQCRQ, UQCR11, MT-CYB and 7 moremitochondrial matrix, mitochondrial intermembrane space, cytosol