beta-carboline

1. beta-carboline hydrolysis

No catalyst recordedcytosol

1. beta-carboline hydrolysis
2. L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating)

Catalysed by TPH1, TPH2cytosol

1. beta-carboline hydrolysis
2. transport of leucine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin

Catalysed by TPH1, TPH2cytosol

1. beta-carboline hydrolysis
2. transport of homoserine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 3 routes

1. beta-carboline hydrolysis
2. transport of histidine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A6cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. transport of citrulline and tryptophan (cytosol to extracellular)

Catalysed by SLC7A9, SLC3A1, SLC7A6cytosol, extracellular space

1. beta-carboline hydrolysis
2. transport of tryptophan and valine (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of arginine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A6cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. PROTEIN_BS

No catalyst recordedcytosol

1. beta-carboline hydrolysis
2. L-tryptophan decarboxy-lyase

Catalysed by DDCcytosol

1. beta-carboline hydrolysis
2. transport of threonine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of isoleucine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of proline and tryptophan (cytosol to extracellular)

Catalysed by ABCA1, SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. Transport of 3-Hydroxy-L-Kynurenine

Catalysed by SLC7A5cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. transport of cysteine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. L-tryptophan + O2 + H2O = indole-3-pyruvate + H2O2 + NH4(+)

Catalysed by IL4I1cytosolOne of 2 routes

1. beta-carboline hydrolysis
2. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin

Catalysed by TPH1, TPH2cytosol

1. beta-carboline hydrolysis
2. transport of tryptophan and tyrosine (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of lysine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A6cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. transport of glutamine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. L-Tryptophan, Tetrahydrobiopterin:Oxygen Oxidoreductase (5-Hydroxylating)

Catalysed by TPH1, TPH2cytosolOne of 2 routes

1. beta-carboline hydrolysis
2. L-Tryptophan -tRNA(Trp) ligase (AMP-forming)

Catalysed by WARS1cytosol

1. beta-carboline hydrolysis
2. Transport of L-Tryptophan by Atb0 Transporter

Catalysed by SLC6A14cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. L-tryptophan(out) + L-aspartate(in) = L-tryptophan(in) + L-aspartate(out)

Catalysed by SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. beta-carboline hydrolysis
2. L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)

Catalysed by IDO1, TDO2, IDO2cytosol

1. beta-carboline hydrolysis
2. transport of ornithine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A6cytosol, extracellular spaceOne of 2 routes

1. beta-carboline hydrolysis
2. transport of glycine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 5 routes

1. beta-carboline hydrolysis
2. transport of methionine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of alanine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

1. beta-carboline hydrolysis
2. transport of asparagine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 3 routes

1. beta-carboline hydrolysis
2. transport of phenylalanine and tryptophan (cytosol to extracellular)

Catalysed by SLC7A5cytosol, extracellular spaceOne of 6 routes

1. beta-carboline hydrolysis
2. L-tryptophan + O2 = N-formyl-L-kynurenine

Catalysed by IDO1, TDO2, IDO2cytosol

1. beta-carboline hydrolysis
2. Transport of L-Tryptophan by Atb0 Transporter
3. Carnitine Transport by Atb0

Catalysed by SLC6A14cytosol, extracellular space

1. beta-carboline hydrolysis
2. transport of glycine and tryptophan (cytosol to extracellular)
3. bile acid-CoA: amino acid N-acyltransferase

Catalysed by SLC7A5, BAATcytosol, extracellular space, peroxisomeOne of 40 routes