Compound
L-cysteinylglycine
The zwitterion of L-cysteinylglycine resulting from the transfer of a proton from the hydroxy group of glycine to the amino group of cysteine. Major microspecies at pH 7.3.
Definition from ChEBI (CHEBI:61694), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound
- Formula
- C5H10N2O3S
- Mass
- 178.213 g/mol
- Charge
- 0
- InChIKey
- ZUKPVRWZDMRIEO-VKHMYHEASA-N
- SMILES
- [NH3+][C@@H](CS)C(=O)NCC(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
15 entities
15 entities reached.
0 reported hops15 assembled from the scaffold
- GGT1ProteinUNIPROT:P19440substrate ofInferred only34 paths34 endpoints
- ANPEPProteinUNIPROT:P15144substrate ofInferred only26 paths13 endpoints
- GGT5ProteinUNIPROT:P36269substrate ofInferred only23 paths23 endpoints
- NPEPPSProteinUNIPROT:P55786substrate ofInferred only12 paths6 endpoints
- CHAC1ProteinUNIPROT:Q9BUX1substrate ofInferred only10 paths10 endpoints
- GGT6ProteinUNIPROT:Q6P531substrate ofInferred only9 paths9 endpoints
- CNDP2ProteinUNIPROT:Q96KP4substrate ofInferred only9 paths9 endpoints
- GGT7ProteinUNIPROT:Q9UJ14substrate ofInferred only9 paths9 endpoints
- IFI30ProteinUNIPROT:P13284substrate ofInferred only9 paths9 endpoints
- SLC15A2ProteinUNIPROT:Q16348transported byInferred only5 paths5 endpoints
- CHAC2ProteinUNIPROT:Q8WUX2substrate ofInferred only5 paths5 endpoints
- NIT1ProteinUNIPROT:Q86X76substrate ofInferred only3 paths3 endpoints
What the reference databases state
Statements
25 statements
25 statements · 2 reference databases · Subject: L-cysteinylglycine · Sources: Human-GEM, Rhea
- CHEBI:16856 is converted to L-cysteinylglycineCompoundHuman-GEM MAR04175Inferred only
- CHEBI:16856 is converted to L-cysteinylglycineCompoundHuman-GEM MAR04176Inferred only
- glutathione is converted to L-cysteinylglycineCompoundRhea RHEA:28807Inferred only
- N-(4-oxoglutaryl)-L-cysteinylglycine is converted to L-cysteinylglycineCompoundRhea RHEA:54532Inferred only
- L-cysteinylglycine is converted to N-(4-oxoglutaryl)-L-cysteinylglycineCompoundRhea RHEA:54532Inferred only
- L-cysteinylglycine is a substrate of ANPEPProteinHuman-GEM MAR04328Inferred only
- L-cysteinylglycine is a substrate of ANPEPProteinHuman-GEM MAR04329Inferred only
- L-cysteinylglycine is a substrate of CHAC1ProteinRhea RHEA:47724Inferred only
- L-cysteinylglycine is a substrate of CHAC2ProteinRhea RHEA:47724Inferred only
- L-cysteinylglycine is a substrate of CNDP2ProteinRhea RHEA:28783Inferred only
- L-cysteinylglycine is a substrate of GGT1ProteinHuman-GEM MAR04937Inferred only
- L-cysteinylglycine is a substrate of GGT5ProteinHuman-GEM MAR04937Inferred only
Show the remaining 13
- L-cysteinylglycine is a substrate of GGT6ProteinHuman-GEM MAR04937Inferred only
- L-cysteinylglycine is a substrate of GGT7ProteinHuman-GEM MAR04937Inferred only
- L-cysteinylglycine is a substrate of GGTLC2ProteinHuman-GEM MAR04937Inferred only
- L-cysteinylglycine is a substrate of GGTLC3ProteinHuman-GEM MAR04937Inferred only
- L-cysteinylglycine is a substrate of IFI30ProteinRhea RHEA:86315Inferred only
- L-cysteinylglycine is a substrate of LAP3ProteinHuman-GEM MAR04328Inferred only
- L-cysteinylglycine is a substrate of LAP3ProteinHuman-GEM MAR04329Inferred only
- L-cysteinylglycine is a substrate of LAP3ProteinRhea RHEA:28783Inferred only
- L-cysteinylglycine is a substrate of NIT1ProteinRhea RHEA:54532Inferred only
- L-cysteinylglycine is a substrate of NPEPPSProteinHuman-GEM MAR04328Inferred only
- L-cysteinylglycine is a substrate of NPEPPSProteinHuman-GEM MAR04329Inferred only
- L-cysteinylglycine is transported by SLC15A1ProteinHuman-GEM MAR07680Inferred only
- L-cysteinylglycine is transported by SLC15A2ProteinHuman-GEM MAR07680Inferred only
Reactions
13 reactions
CHEBI:16856+waterL-cysteinylglycine+L-glutamate(1-)
Catalysed by GGT5 or GGT1 or GGTLC2 or GGT7 or GGT6 or GGTLC3
Reaction pageLeft to rightBalancedEC 2.3.2.2, 3.4.11.4cytosol
Human-GEM MAR04175CC BY 4.0Reference data
CHEBI:16856+waterL-cysteinylglycine+L-glutamate(1-)
Catalysed by GGT5 or GGT1 or GGTLC2 or GGT7 or GGT6 or GGTLC3
Reaction pageLeft to rightBalancedEC 2.3.2.2, 3.4.11.4extracellular space
Human-GEM MAR04176CC BY 4.0Reference data
L-cysteinylglycine+waterL-cysteine+glycine
Catalysed by LAP3 or NPEPPS or ANPEP
Reaction pageLeft to rightBalancedEC 3.4.11.1, 3.4.11.2cytosol
Human-GEM MAR04328CC BY 4.0Reference data
L-cysteinylglycine+waterL-cysteine+glycine
Catalysed by LAP3 or NPEPPS or ANPEP
Reaction pageLeft to rightBalancedEC 3.4.11.1, 3.4.11.2extracellular space
Human-GEM MAR04329CC BY 4.0Reference data
L-alanine+CHEBI:16856L-cysteinylglycine+MAM01930c
Catalysed by GGT5 or GGT1 or GGTLC2 or GGT7 or GGT6 or GGTLC3
Reaction pageReversibleBalancedEC 2.3.2.2cytosol
Human-GEM MAR04937CC BY 4.0Reference data
L-cysteinylglycine+2protonL-cysteinylglycine+2proton
Transported by SLC15A1 or SLC15A2
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR07680CC BY 4.0Reference data
L-alanine+CHEBI:16856gamma-Glu-Ala+L-cysteinylglycine
Catalysed by GGT5 or GGT1 or GGTLC2 or GGT7 or GGTLC1 or GGT6
Reaction pageLeft to rightBalancedEC 2.3.2.2cytosol, extracellular space
Human-GEM MAR08769CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09279CC BY 4.0Reference data
L-cysteinylglycine+waterL-cysteine+glycine
Reaction pageLeft to rightBalanced
Rhea RHEA:28783CC BY 4.0Reference data
glutathione+waterL-cysteinylglycine+L-glutamate(1-)
Catalysed by GGT3P or GGT1 or GGT5 or GGT6 or GGT7
Reaction pageLeft to rightBalanced
Rhea RHEA:28807CC BY 4.0Reference data
glutathioneL-cysteinylglycine+5-oxo-L-proline
Reaction pageDirection not assertedBalanced
Rhea RHEA:47724CC BY 4.0Reference data
N-(4-oxoglutaryl)-L-cysteinylglycine+waterL-cysteinylglycine+2-oxoglutarate(2-)
Catalysed by NIT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:54532CC BY 4.0Reference data
Where it reaches
2 systems, 2 regions, 6 tissues, 6 transporter routes — routes, not measurements: transporters known to carry L-cysteinylglycine are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: L-cysteinylglycine
- Also called
- Cys-GlyCys-Gly zwitterion