Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

Search the graph

Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Articles Pathways Processes Anatomy Cell types Organisms Materials Assessments

Reaction

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water

Left to right · Balance undeterminable

Inferred

Reference data, not a finding. Evidence key

Catalysts

PTGES
MGST3
GPX1
GPX2
GPX4
MGST2

Rhea RHEA:48620·2026-08-19·CC BY 4.0Reference data

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments

How it works

Mission
Method
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

Reaction

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water

Left to right · Balance undeterminable

Inferred

Reference data, not a finding. Evidence key

Catalysts

PTGES
MGST3
GPX1
GPX2
GPX4
MGST2

Rhea RHEA:48620·2026-08-19·CC BY 4.0Reference data

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione→(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water

Catalysts

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione→(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water

Catalysts

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+2glutathione(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate+glutathione disulfide+water