leukotriene F4

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

410 compounds within 3 steps: 4 in 1, 55 in 2, 351 in 3

One step

2,4-dinitrophenyl-S-glutathioneReach from here →
1. transport of leukotriene F4 (cytosol to extracellular)
Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes
CHEBI:15650Reach from here →
1. leukotriene F4 hydrolysis
No catalyst recordedcytosol
CHEBI:16856Reach from here →
1. transport of GSH and leukotriene F4 (cytosol to extracellular)
No catalyst recordedextracellular space, cytosolOne of 2 routes
leukotriene C4Reach from here →
1. leukotriene C4 hydrolysis
No catalyst recordedcytosol

Two steps

CHEBI:1146900Reach from here →
1. leukotriene F4 hydrolysis
2. N-acetyl-LTE4 to leukotriene E4 conversion
Catalysed by ZDHHC11B, NAA10, ESCO2, ESCO1 and 28 morecytosolOne of 2 routes
tauroursodeoxycholateReach from here →
1. transport of leukotriene F4 (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosol

One of 4 routes

glycoursodeoxycholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by PTGES, MGST3, GSTA4, GSTZ1 and 17 moreextracellular space, cytosolOne of 4 routes

prostaglandin E3Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin A2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin B1Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

acetylcholineReach from here →

Catalysed by SLCO1B1, SLCO1B3extracellular space, cytosolOne of 4 routes

bromideReach from here →

Catalysed by MGST3, GSTA4, GSTA1, GSTA2 and 13 moreextracellular space, cytosolOne of 2 routes

lithocholic acidReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

bilirubin IXalphaReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

taurolithocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:17208Reach from here →

No catalyst recordedextracellular space, cytosol

homocysteineReach from here →

No catalyst recordedextracellular space, cytosol

L-cysteineReach from here →

No catalyst recordedextracellular space, cytosol

5(S)-HETEReach from here →

Catalysed by GPX5, GPX1, GPX2, GPX3 and 5 moreextracellular space, cytosolOne of 2 routes

CHEBI:28666Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 8 routes

glycocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

cholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

serotoninReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

chenodeoxycholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

taurocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

glycolithocholic acidReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

gamma-Glu-AlaReach from here →

Catalysed by GGT1, GGT5, GGTLC2, GGT6 and 2 moreextracellular space, cytosol

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

glycineReach from here →

No catalyst recordedcytosolOne of 2 routes

prostaglandin E1Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin I2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin F2alphaReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin H2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin D2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by GPX5, GPX1, GPX2, GPX3 and 5 moreextracellular space, cytosol

leukotriene A4Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 5 routes

(R)-S-lactoylglutathioneReach from here →

Catalysed by GLO1, GLOD4extracellular space, cytosolOne of 2 routes

S-formylglutathioneReach from here →

Catalysed by ADH1C, ADH1A, ADH5, ADH6 and 2 moreextracellular space, cytosol

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2cytosol

glutathione disulfideReach from here →

Catalysed by GPX5, GPX1, GPX2, GPX3 and 5 moreextracellular space, cytosolOne of 13 routes

taurolithocholate 3-sulfateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

histamineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

L-thyroxineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

S-sulfanylglutathioneReach from here →

Catalysed by SQORextracellular space, cytosol, mitochondrial matrix

dopamineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

glycolithocholate 3-sulfateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

estrone 3-sulfateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes