Compound
prostaglandin B1
A prostaglandin carboxylic acid anion that is the conjugate base of prostaglandin B1, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:133393), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C20H31O4
- Mass
- 335.464 g/mol
- Charge
- -1
- InChIKey
- YBHMPNRDOVPQIN-VSOYFRJCSA-M
- SMILES
- CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)[O-])C(=O)CC1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- UGT1A1ProteinUNIPROT:P22309metabolized byInferred only25 paths25 endpoints
- UGT1A9ProteinUNIPROT:O60656metabolized byInferred only24 paths24 endpoints
- UGT2B7ProteinUNIPROT:P16662metabolized byInferred only16 paths16 endpoints
- SLCO2A1ProteinUNIPROT:Q92959transported byInferred only14 paths13 endpoints
- UGT1A10ProteinUNIPROT:Q9HAW8metabolized byInferred only14 paths14 endpoints
- SLCO1B1ProteinUNIPROT:Q9Y6L6transported byInferred only9 paths2 endpoints
What the reference databases state
Statements
10 statements
10 statements · 2 reference databases · Subject: prostaglandin B1 · Sources: Human-GEM, Rhea
- prostaglandin B1 is converted to 15-O-(beta-D-glucuronosyl)-prostaglandin B1CompoundRhea RHEA:79935Inferred only
- prostaglandin B1 is metabolised by UGT1A1ProteinRhea RHEA:79935Inferred only
- prostaglandin B1 is metabolised by UGT1A10ProteinRhea RHEA:79935Inferred only
- prostaglandin B1 is metabolised by UGT1A9ProteinRhea RHEA:79935Inferred only
- prostaglandin B1 is metabolised by UGT2B7ProteinRhea RHEA:79935Inferred only
- prostaglandin B1 is transported by SLC22A10ProteinHuman-GEM MAR06261Inferred only
- prostaglandin B1 is transported by SLCO1B1ProteinHuman-GEM MAR06170Inferred only
- prostaglandin B1 is transported by SLCO1B1ProteinHuman-GEM MAR06171Inferred only
- prostaglandin B1 is transported by SLCO1B1ProteinHuman-GEM MAR06169Inferred only
- prostaglandin B1 is transported by SLCO2A1ProteinHuman-GEM MAR06226Inferred only
Reactions
9 reactions
prostaglandin B1MAM02780c
Reaction pageReversibleBalancedEC 5.3.3.9cytosol
Human-GEM MAR01402CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR04215CC BY 4.0Reference data
MAM01980c+hydrogencarbonate+prostaglandin B1MAM01980e+hydrogencarbonate+prostaglandin B1
Transported by SLCO1B1
Reaction pageReversibleBalance undeterminablecytosol, extracellular space
Human-GEM MAR06169CC BY 4.0Reference data
hydrogencarbonate+prostaglandin B1+2,4-dinitrophenyl-S-glutathionehydrogencarbonate+prostaglandin B1+2,4-dinitrophenyl-S-glutathione
Transported by SLCO1B1
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06170CC BY 4.0Reference data
hydrogencarbonate+prostaglandin B1+MAM02901chydrogencarbonate+prostaglandin B1+MAM02901e
Transported by SLCO1B1
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06171CC BY 4.0Reference data
CHEBI:16856+hydrogencarbonate+prostaglandin B1CHEBI:16856+hydrogencarbonate+prostaglandin B1
Transported by SLCO2A1
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06226CC BY 4.0Reference data
prostaglandin B1prostaglandin B1
Transported by SLC22A10
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06261CC BY 4.0Reference data
CHEBI:57399prostaglandin B1
Reaction pageDirection not assertedBalanced
Rhea RHEA:50552CC BY 4.0Reference data
prostaglandin B1+UDP-alpha-D-glucuronate15-O-(beta-D-glucuronosyl)-prostaglandin B1+UDP+hydron
Catalysed by UGT1A9 or UGT2B7 or UGT1A1 or UGT1A10
Reaction pageLeft to rightBalanced
Rhea RHEA:79935CC BY 4.0Reference data
Where it reaches
5 systems, 8 regions, 15 tissues, 15 transporter routes — routes, not measurements: transporters known to carry prostaglandin B1 are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: prostaglandin B1
- Also called
- PGB1
- Systematic name
- (13E,15S)-15-hydroxy-9-oxoprosta-8(12),13-dien-1-oate