leukotriene C4

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

585 compounds within 3 steps: 8 in 1, 152 in 2, 425 in 3

One step

leukotriene F4Reach from here →
1. leukotriene C4 hydrolysis
No catalyst recordedcytosolOne of 2 routes
2,4-dinitrophenyl-S-glutathioneReach from here →
1. transport of leukotriene C4 (cytosol to extracellular)
Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes
CHEBI:16856Reach from here →
1. transport of GSH and leukotriene C4 (cytosol to extracellular)
Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes
CHEBI:28666Reach from here →
1. gamma-glutamyltransferase (leukotriene C4)
Catalysed by GGT1, GGT5, GGTLC2, GGT6 and 2 moreextracellular spaceOne of 3 routes
glycineReach from here →
1. leukotriene C4 hydrolysis
No catalyst recordedcytosolOne of 2 routes
leukotriene A4Reach from here →
1. leukotriene C4 = leukotriene A4 + glutathione
Catalysed by MGST3, GSTM4, LTC4S, MGST2
glutathioneReach from here →
1. leukotriene C4 = leukotriene A4 + glutathione
Catalysed by MGST3, GSTM4, LTC4S, MGST2
leukotriene D4Reach from here →
1. leukotriene C4 + H2O = leukotriene D4 + L-glutamate
Catalysed by GGT1, GGT5

Two steps

CHEBI:1146900Reach from here →
1. leukotriene C4 hydrolysis
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by BAATcytosol, peroxisomeOne of 28 routes
N(omega)-methyl-L-arginineReach from here →
1. leukotriene C4 hydrolysis
2. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine
Catalysed by AGXT2cytosol
2-phenylpropan-2-olReach from here →

leukotriene C4 = leukotriene A4 + glutathione

cumene hydroperoxide + 2 glutathione = 2-phenylpropan-2-ol + glutathione disulfide + H2O

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 4 more

a hydroxy polyunsaturated fatty acidReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 3 more

tauroursodeoxycholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 5 routes

glycoursodeoxycholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 7 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 2 more

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by SLCO1B1, PTGES, MGST3, GSTA4 and 18 moreextracellular space, cytosolOne of 5 routes

prostaglandin E3Reach from here →

Catalysed by SLCO1B1, SLCO2A1extracellular space, cytosolOne of 4 routes

prostaglandin A2Reach from here →

Catalysed by SLCO1B1, SLCO2A1extracellular space, cytosolOne of 4 routes

prostaglandin B1Reach from here →

Catalysed by SLCO1B1, SLCO2A1extracellular space, cytosolOne of 4 routes

prostaglandin A2-S-(R)-glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 2 more

prostaglandin A2-S-(S)-glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 2 more

prostaglandin J2-S-(R)-glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 3 more

prostaglandin J2-S-(S)-glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 2 more

N-(9Z-octadecenoyl)glycineReach from here →

Catalysed by GLYATL3, GLYATL2cytosol

N-octadecanoylglycineReach from here →

Catalysed by GLYATL2cytosol

N-(9Z-hexadecenoyl)-glycineReach from here →

Catalysed by GLYATL2cytosol

(13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoateReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2

S-methyl glutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 more

N-hexadecanoylglycineReach from here →

Catalysed by GLYATL3cytosol

N-dodecanoylglycineReach from here →

Catalysed by GLYATL2cytosol

N-decanoylglycineReach from here →

Catalysed by GLYATL2cytosol

N-octanoylglycineReach from here →

Catalysed by GLYATL2cytosol

N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →

Catalysed by GARTcytosol

L-cystine-bis-glycineReach from here →

Catalysed by DPEP1, DPEP2cytosol

glycyldehydrophenylalanineReach from here →

Catalysed by DPEP1cytosol

S-adenosylglutathioneReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 more

an N-(fatty acyl)-glycineReach from here →

Catalysed by GLYATL2cytosol

N-(9Z,12Z-octadecadienoyl)-glycineReach from here →

Catalysed by GLYATL2cytosol

acetylcholineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:15570Reach from here →

Catalysed by SLC3A2, SLC7A10cytosol, extracellular spaceOne of 2 routes

L-leucineReach from here →

Catalysed by SLC7A5cytosol, extracellular spaceOne of 5 routes

CHEBI:15611Reach from here →

Catalysed by GNMTcytosol

CHEBI:15650Reach from here →

Catalysed by GGT1, GGT5, GGTLC2, GGT6 and 4 moreextracellular spaceOne of 7 routes

CHEBI:15699Reach from here →

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes

bromideReach from here →

Catalysed by SLCO1B1, MGST3, GSTA4, GSTA1 and 14 moreextracellular space, cytosolOne of 2 routes

CHEBI:15971Reach from here →

Catalysed by SLC7A6cytosol, extracellular spaceOne of 2 routes

a halide anionReach from here →

Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 21 more

lithocholic acidReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

L-citrullineReach from here →

Catalysed by SLC7A9, SLC3A1, SLC7A6cytosol, extracellular space

L-valineReach from here →

Catalysed by SLC7A5cytosol, extracellular spaceOne of 4 routes