17beta-hydroxy-androst-5-en-3-one

1. 17beta-hydroxy-androst-5-en-3-one = testosterone

Catalysed by HSD3B1

1. androst-5-en-3beta,17beta-diol + NAD(+) = 17beta-hydroxy-androst-5-en-3-one + NADH + H(+)

Catalysed by HSD3B1

1. 17beta-hydroxy-androst-5-en-3-one = testosterone
2. 17beta-hydroxysteroid UDP-glucuronosyltransferase

Catalysed by HSD3B1, UGT2B17, UGT2B7, UGT1A1 and 3 moreendoplasmic reticulumOne of 2 routes

1. 17beta-hydroxy-androst-5-en-3-one = testosterone
2. testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 1beta-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by HSD3B1, CYP3A4

1. 17beta-hydroxy-androst-5-en-3-one = testosterone
2. cytochrome P450 (testosterone)
3. transport of 2-hydroxybutyrate and formate (cytosol to extracellular)

Catalysed by HSD3B1, CYP19A1, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

1. 17beta-hydroxy-androst-5-en-3-one = testosterone
2. cytochrome P450 (testosterone)
3. 17beta-estradiol + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)