Compound
testosterone 17-O-(beta-D-glucuronate)
A steroid glucuronide anion that is the conjugate base of testosterone 17-O-(β-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.
Definition from ChEBI (CHEBI:136639), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C25H35O8
- Mass
- 463.547 g/mol
- Charge
- -1
- InChIKey
- NIKZPECGCSUSBV-HMAFJQTKSA-M
- SMILES
- [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O[C@@H]3O[C@H](C(=O)[O-])[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]21[H]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: testosterone 17-O-(beta-D-glucuronate) · Sources: Human-GEM, Rhea
- testosterone is converted to testosterone 17-O-(beta-D-glucuronate)CompoundHuman-GEM MAR07959Inferred only
- testosterone is converted to testosterone 17-O-(beta-D-glucuronate)CompoundRhea RHEA:52456Inferred only
- testosterone 17-O-(beta-D-glucuronate) is converted to testosterone 17-O-(3-sulfo-beta-D-glucuronate)CompoundRhea RHEA:68684Inferred only
- testosterone 17-O-(beta-D-glucuronate) is a substrate of CHST10ProteinRhea RHEA:68684Inferred only
- testosterone 17-O-(beta-D-glucuronate) is transported by ABCC1ProteinHuman-GEM MAR08850Inferred only
- testosterone 17-O-(beta-D-glucuronate) is transported by ABCC2ProteinRhea RHEA:86847Inferred only
Reactions
7 reactions
testosterone+UDP-alpha-D-glucuronatetestosterone 17-O-(beta-D-glucuronate)+UDP
Catalysed by UGT2B28 or UGT2B7 or UGT2B17 or UGT1A1 or UGT1A8 or UGT1A10
Reaction pageLeft to rightBalancedEC 2.4.1.17endoplasmic reticulum
Human-GEM MAR07959CC BY 4.0Reference data
ATP+water+testosterone 17-O-(beta-D-glucuronate)ADP+proton+phosphate(3-)+testosterone 17-O-(beta-D-glucuronate)
Transported by ABCC1
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR08850CC BY 4.0Reference data
testosterone 17-O-(beta-D-glucuronate)testosterone 17-O-(beta-D-glucuronate)
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR08851CC BY 4.0Reference data
testosterone 17-O-(beta-D-glucuronate)
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09430CC BY 4.0Reference data
testosterone+UDP-alpha-D-glucuronatetestosterone 17-O-(beta-D-glucuronate)+UDP+hydron
Catalysed by UGT2B17 or UGT2A1
Reaction pageLeft to rightBalanced
Rhea RHEA:52456CC BY 4.0Reference data
testosterone 17-O-(beta-D-glucuronate)+3'-phosphoadenylyl sulfatetestosterone 17-O-(3-sulfo-beta-D-glucuronate)+adenosine 3',5'-bisphosphate+hydron
Catalysed by CHST10
Reaction pageLeft to rightBalanced
Rhea RHEA:68684CC BY 4.0Reference data
testosterone 17-O-(beta-D-glucuronate)+ATP(4-)+watertestosterone 17-O-(beta-D-glucuronate)+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC2
Reaction pageLeft to rightBalanced
Rhea RHEA:86847CC BY 4.0Reference data
Where it reaches
1 system, 4 regions, 6 tissues, 6 transporter routes — routes, not measurements: transporters known to carry testosterone 17-O-(beta-D-glucuronate) are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: testosterone 17-O-(beta-D-glucuronate)
- Systematic name
- 3-oxoandrost-4-en-17beta-yl beta-D-glucopyranosiduronate3-oxoandrost-4-en-17β-yl β-D-glucopyranosiduronate