Compound
5beta-dihydrotestosterone
A 17β-hydroxyandrostan-3-one that has β- configuration at position 5. It is a metabolite of testosterone.
Definition from ChEBI (CHEBI:2150), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C19H30O2
- Mass
- 290.447 g/mol
- Charge
- 0
- InChIKey
- NVKAWKQGWWIWPM-MISPCMORSA-N
- SMILES
- [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](O)CC[C@@]34[H])[C@@]1(C)CCC(=O)C2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
0 reported hops3 assembled from the scaffold
- AKR1D1ProteinUNIPROT:P51857substrate ofInferred only15 paths15 endpoints
- DHRS4ProteinUNIPROT:Q9BTZ2substrate ofInferred only7 paths7 endpoints
- testosteroneCompoundCHEBI:17347converted toInferred only2 paths2 endpoints
What the reference databases state
Statements
4 statements
4 statements · 1 reference database · Subject: 5beta-dihydrotestosterone · Sources: Rhea
- 5beta-dihydrotestosterone is converted to testosteroneCompoundRhea RHEA:46636Inferred only
- testosterone is converted to 5beta-dihydrotestosteroneCompoundRhea RHEA:46636Inferred only
- 5beta-dihydrotestosterone is a substrate of AKR1D1ProteinRhea RHEA:46636Inferred only
- 5beta-dihydrotestosterone is a substrate of DHRS4ProteinRhea RHEA:69012Inferred only
Reactions
3 reactions
5beta-dihydrotestosterone+NADP(3-)testosterone+NADPH(4-)+hydron
Catalysed by AKR1D1
Reaction pageDirection not assertedBalanced
Rhea RHEA:46636CC BY 4.0Reference data
5beta-dihydrotestosterone+NADPH(4-)+hydronCHEBI:36715+NADP(3-)
Catalysed by DHRS4
Reaction pageLeft to rightBalanced
Rhea RHEA:69012CC BY 4.0Reference data
5beta-dihydrotestosterone+NADPH(4-)+hydronCHEBI:36714+NADP(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:69028CC BY 4.0Reference data
Other names
16 names
Resolves to: 5beta-dihydrotestosterone
- Also called
- (5beta,17beta)-17-hydroxyandrostan-3-one(5beta,8alpha,17beta)-17-hydroxyandrostan-3-one(5β,17β)-17-hydroxyandrostan-3-one(5β,8α,17β)-17-hydroxyandrostan-3-one17beta-hydroxy-5beta-androstan-3-one17beta-hydroxyetiocholan-3-one17β-hydroxyetiocholan-3-one5-beta-DHT5beta-androstan-17beta-ol-3-one5beta,17beta-hydroxyandrostan-3-one5β-androstan-17β-ol-3-one5β,17β-hydroxyandrostan-3-oneetiocholan-17-beta-ol-3-oneST 19:1;O2
- Systematic name
- 17beta-hydroxy-5betaandrostan-3-one17β-hydroxy-5βandrostan-3-one