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Proteins/UNIPROT:P49189
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines..
Function from UniProtKB (P49189), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
169 statements
169 statements · 6 reference databases · Subject: ALDH9A1 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
42 reactions
MAM01981c+water+NAD(+)(R)-glycerate+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR00456CC BY 4.0Reference data
MAM01981m+water+
11 names
Resolves to: ALDH9A1
Reaction pageLeft to rightBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR00459CC BY 4.0Reference data
MAM00585c+2proton+NADH(2-)MAM00600c+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3cytosol
Human-GEM MAR01132CC BY 4.0Reference data
MAM00585m+2proton+NADH(2-)MAM00600m+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR01133CC BY 4.0Reference data
MAM00585r+2proton+NADH(2-)MAM00600r+water+NAD(+)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3endoplasmic reticulum
Human-GEM MAR01134CC BY 4.0Reference data
MAM00601x+water+NAD(+)MAM00586x+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3peroxisome
Human-GEM MAR01289CC BY 4.0Reference data
MAM00756c+water+NAD(+)MAM00758c+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageReversibleBalancedEC 1.2.1.3cytosol
Human-GEM MAR01692CC BY 4.0Reference data
2-methyl-3-oxopropanoic acid+water+NAD(+)2proton+MAM02479m+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or AOX1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3, 1.2.3.1mitochondrial matrix
Human-GEM MAR03759CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+2proton+NADH(2-)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+water+NAD(+)
Catalysed by ALDH3A1 or ALDH9A1
Reaction pageReversibleBalancedEC 1.2.1.3cytosol
Human-GEM MAR03815CC BY 4.0Reference data
3-aminopropanal+water+NADP(3-)beta-alanine+2proton+NADPH(4-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR04079CC BY 4.0Reference data
(5-hydroxyindol-3-yl)acetaldehyde+water+NAD(+)(5-hydroxyindol-3-yl)acetate+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR04559CC BY 4.0Reference data
CHEBI:17769+water+NADP(3-)4-aminobutanoate+2proton+NADPH(4-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR04605CC BY 4.0Reference data