Compound
11beta,17beta-dihydroxyandrost-4-ene-3-one
An androstanoid that is testosterone carrying an additional hydroxy substituent at the 11β-position.
Definition from ChEBI (CHEBI:81481), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound
- Formula
- C19H28O3
- Mass
- 304.43 g/mol
- Charge
- 0
- InChIKey
- YQDZGFAYWGWSJK-SLMGBJJTSA-N
- SMILES
- [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]1(C)[C@@H](O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Chemical structure
- 11beta,17beta-dihydroxyandrost-4-ene-3-one has the functional parent testosteroneCompoundChEBI CHEBI:81481Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: 11beta,17beta-dihydroxyandrost-4-ene-3-one · Sources: Rhea
- 11beta-hydroxyandrost-4-ene-3,17-dione is converted to 11beta,17beta-dihydroxyandrost-4-ene-3-oneCompoundRhea RHEA:53488Inferred only
- 11beta,17beta-dihydroxyandrost-4-ene-3-one is a substrate of HSD11B1ProteinRhea RHEA:86451Inferred only
- 11beta,17beta-dihydroxyandrost-4-ene-3-one is a substrate of HSD11B2ProteinRhea RHEA:69368Inferred only
Reactions
5 reactions
testosterone+reduced [NADPH--hemoprotein reductase]+dioxygen11beta,17beta-dihydroxyandrost-4-ene-3-one+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP3A4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53444CC BY 4.0Reference data
11beta-hydroxyandrost-4-ene-3,17-dione+NADPH(4-)+hydron11beta,17beta-dihydroxyandrost-4-ene-3-one+NADP(3-)
Catalysed by HSD17B3
Reaction pageLeft to rightBalanced
Rhea RHEA:53488CC BY 4.0Reference data
11beta,17beta-dihydroxyandrost-4-ene-3-one+NAD(1-)CHEBI:34133+NADH(2-)+hydron
Catalysed by HSD11B2
Reaction pageLeft to rightBalanced
Rhea RHEA:69368CC BY 4.0Reference data
11beta,17beta-dihydroxyandrost-4-ene-3-one+NADP(3-)CHEBI:34133+NADPH(4-)+hydron
Catalysed by HSD11B1
Reaction pageReversibleBalanced
Rhea RHEA:86451CC BY 4.0Reference data
testosterone+2reduced [adrenodoxin]+dioxygen+2hydron11beta,17beta-dihydroxyandrost-4-ene-3-one+2oxidized [adrenodoxin]+water
Catalysed by CYP11B1 or CYP11B2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:86455CC BY 4.0Reference data
Other names
8 names
Resolves to: 11beta,17beta-dihydroxyandrost-4-ene-3-one
- Also called
- (11beta,17beta)-11,17-dihydroxyandrost-4-en-3-one(11β,17β)-11,17-dihydroxyandrost-4-en-3-one11-Hydroxytestosterone11beta-Hydroxytestosterone11beta,17beta-Dihydroxy-4-androsten-3-one4-androstene-11beta,17beta-diol-3-oneST 19:2;O3
- Systematic name
- 11β,17β-dihydroxyandrost-4-ene-3-one