Compound
testosterone
No description recorded for this entry yet. Everything this graph holds about testosterone is below.
CHEBI:17347ChEBI
Structure
- Class
- Organic compound
- Formula
- C19H28O2
- Mass
- 288.431 g/mol
- Charge
- 0
- InChIKey
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N
- SMILES
- [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says testosterone moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
30 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
30 entities
30 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops30 assembled from the scaffold
- CYP3A4ProteinUNIPROT:P08684metabolized byInferred only192 paths48 endpoints
- AKR1C3ProteinUNIPROT:P42330substrate ofInferred only114 paths29 endpoints
- HSD17B3ProteinUNIPROT:P37058substrate ofInferred only48 paths16 endpoints
- CYP46A1ProteinUNIPROT:Q9Y6A2metabolized byInferred only48 paths16 endpoints
- HSD17B1ProteinUNIPROT:P14061substrate ofInferred only45 paths15 endpoints
- AKR1C4ProteinUNIPROT:P17516substrate ofInferred only42 paths21 endpoints
- CYP2B6ProteinUNIPROT:P20813metabolized byInferred only40 paths20 endpoints
- HSD17B2ProteinUNIPROT:P37059substrate ofInferred only36 paths12 endpoints
- CYP1B1ProteinUNIPROT:Q16678metabolized byInferred only29 paths29 endpoints
- HSD17B7ProteinUNIPROT:P56937substrate ofInferred only26 paths13 endpoints
- CYP19A1ProteinUNIPROT:P11511metabolized byInferred only25 paths25 endpoints
- CYP11B2ProteinUNIPROT:P19099metabolized byInferred only23 paths23 endpoints
Show the remaining 18
- AKR1C1ProteinUNIPROT:Q04828substrate ofInferred only23 paths23 endpoints
- CYP11B1ProteinUNIPROT:P15538metabolized byInferred only20 paths20 endpoints
- HSD3B1ProteinUNIPROT:P14060substrate ofInferred only18 paths18 endpoints
- SRD5A3ProteinUNIPROT:Q9H8P0substrate ofInferred only18 paths18 endpoints
- HSD17B6ProteinUNIPROT:O14756substrate ofInferred only16 paths4 endpoints
- AKR1C2ProteinUNIPROT:P52895substrate ofInferred only16 paths16 endpoints
- HSD17B10ProteinUNIPROT:Q99714substrate ofInferred only16 paths16 endpoints
- CYP3A5ProteinUNIPROT:P20815metabolized byInferred only15 paths15 endpoints
- AKR1D1ProteinUNIPROT:P51857substrate ofInferred only15 paths15 endpoints
- HSD17B8ProteinUNIPROT:Q92506substrate ofInferred only15 paths5 endpoints
- CYP3A7ProteinUNIPROT:P24462metabolized byInferred only13 paths13 endpoints
- SRD5A2ProteinUNIPROT:P31213substrate ofInferred only13 paths13 endpoints
- HSD17B12ProteinUNIPROT:Q53GQ0substrate ofInferred only12 paths12 endpoints
- SRD5A1ProteinUNIPROT:P18405substrate ofInferred only11 paths11 endpoints
- UGT2B17ProteinUNIPROT:O75795metabolized byInferred only9 paths9 endpoints
- UGT2A1ProteinUNIPROT:P0DTE4metabolized byInferred only8 paths8 endpoints
- AKR1B15ProteinUNIPROT:C9JRZ8substrate ofInferred only5 paths5 endpoints
- HSD17B11ProteinUNIPROT:Q8NBQ5substrate ofInferred only5 paths3 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from testosterone: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Androgenic Steroids". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
64 statements
64 statements in 2 reference databases name testosterone — Human-GEM, Rhea. Press a relation to see only its rows; every count is the rows behind it.
- testosterone is converted to 17beta-hydroxy-5alpha-androstan-3-oneCompoundRhea RHEA:50820Inferred only
- 17beta-hydroxy-5alpha-androstan-3-one is converted to testosteroneCompoundRhea RHEA:50820Inferred only
- testosterone is converted to 17beta-hydroxy-androst-5-en-3-oneCompoundRhea RHEA:56936Inferred only
- 17beta-hydroxy-androst-5-en-3-one is converted to testosteroneCompoundRhea RHEA:56936Inferred only
- 5beta-dihydrotestosterone is converted to testosteroneCompoundRhea RHEA:46636Inferred only
- testosterone is converted to 5beta-dihydrotestosteroneCompoundRhea RHEA:46636Inferred only
- androst-4-ene-3,17-dione is converted to testosteroneCompoundRhea RHEA:14981Inferred only
- androst-4-ene-3,17-dione is converted to testosteroneCompoundRhea RHEA:14929Inferred only
- testosterone is converted to androst-4-ene-3,17-dioneCompoundRhea RHEA:14981Inferred only
- testosterone is converted to androst-4-ene-3,17-dioneCompoundRhea RHEA:14929Inferred only
- testosterone is metabolised by CYP11B1ProteinRhea RHEA:86455Inferred only
- testosterone is metabolised by CYP11B2ProteinRhea RHEA:86455Inferred only
Show the remaining 52
- testosterone is metabolised by CYP19A1ProteinRhea RHEA:38191Inferred only
- testosterone is metabolised by CYP1B1ProteinRhea RHEA:46296Inferred only
- testosterone is metabolised by CYP2B6ProteinRhea RHEA:53196Inferred only
- testosterone is metabolised by CYP2B6ProteinRhea RHEA:46304Inferred only
- testosterone is metabolised by CYP3A4ProteinRhea RHEA:53260Inferred only
- testosterone is metabolised by CYP3A4ProteinRhea RHEA:53444Inferred only
- testosterone is metabolised by CYP3A4ProteinRhea RHEA:53264Inferred only
- testosterone is metabolised by CYP3A4ProteinRhea RHEA:46296Inferred only
- testosterone is metabolised by CYP3A5ProteinRhea RHEA:46296Inferred only
- testosterone is metabolised by CYP3A7ProteinRhea RHEA:46296Inferred only
- testosterone is metabolised by CYP46A1ProteinRhea RHEA:46300Inferred only
- testosterone is metabolised by CYP46A1ProteinRhea RHEA:46304Inferred only
- testosterone is metabolised by CYP46A1ProteinRhea RHEA:46296Inferred only
- testosterone is metabolised by UGT2A1ProteinRhea RHEA:52456Inferred only
- testosterone is metabolised by UGT2B17ProteinRhea RHEA:52456Inferred only
- testosterone is a substrate of AKR1B15ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of AKR1C1ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of AKR1C2ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of AKR1C3ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of AKR1C3ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of AKR1C3ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of AKR1C3ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of AKR1C4ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of AKR1C4ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of AKR1D1ProteinRhea RHEA:46636Inferred only
- testosterone is a substrate of DHRS1ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of HSD17B1ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of HSD17B1ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B1ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B10ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of HSD17B11ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B11ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B12ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B2ProteinHuman-GEM MAR07955Inferred only
- testosterone is a substrate of HSD17B2ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of HSD17B2ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B3ProteinRhea RHEA:14981Inferred only
- testosterone is a substrate of HSD17B3ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B3ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B6ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B6ProteinHuman-GEM MAR07955Inferred only
- testosterone is a substrate of HSD17B6ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of HSD17B6ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B7ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B7ProteinHuman-GEM MAR01974Inferred only
- testosterone is a substrate of HSD17B8ProteinRhea RHEA:14929Inferred only
- testosterone is a substrate of HSD17B8ProteinHuman-GEM MAR01973Inferred only
- testosterone is a substrate of HSD17B8ProteinHuman-GEM MAR07955Inferred only
- testosterone is a substrate of HSD3B1ProteinRhea RHEA:56936Inferred only
- testosterone is a substrate of SRD5A1ProteinRhea RHEA:50820Inferred only
- testosterone is a substrate of SRD5A2ProteinRhea RHEA:50820Inferred only
- testosterone is a substrate of SRD5A3ProteinRhea RHEA:50820Inferred only
Other names
8 names
Every name this graph resolves to testosterone. Searching any of them lands here.
- Also called
- 17beta-hydroxy-4-androsten-3-one4-androsten-17beta-ol-3-one4-androsten-17β-ol-3-oneAndrodermST 19:2;O2Testosteron
- Systematic name
- 17beta-hydroxyandrost-4-en-3-one17β-hydroxyandrost-4-en-3-one