Compound
17beta-hydroxy-androst-5-en-3-one
An androstanoid having a double bond at C-5, an oxo group at C-3 and a hydroxy group with β-configuration at C-17.
Definition from ChEBI (CHEBI:141179), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C19H28O2
- Mass
- 288.431 g/mol
- Charge
- 0
- InChIKey
- SEDRVEWTPRTLOZ-DYKIIFRCSA-N
- SMILES
- [H][C@@]12CC=C3CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
- HSD3B1ProteinUNIPROT:P14060substrate ofInferred only36 paths18 endpoints
- testosteroneCompoundCHEBI:17347converted toInferred only2 paths2 endpoints
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: 17beta-hydroxy-androst-5-en-3-one · Sources: Rhea
- 17beta-hydroxy-androst-5-en-3-one is converted to androst-5-en-3beta,17beta-diolCompoundRhea RHEA:56932Inferred only
- androst-5-en-3beta,17beta-diol is converted to 17beta-hydroxy-androst-5-en-3-oneCompoundRhea RHEA:56932Inferred only
- 17beta-hydroxy-androst-5-en-3-one is converted to testosteroneCompoundRhea RHEA:56936Inferred only
- testosterone is converted to 17beta-hydroxy-androst-5-en-3-oneCompoundRhea RHEA:56936Inferred only
- 17beta-hydroxy-androst-5-en-3-one is a substrate of HSD3B1ProteinRhea RHEA:56932Inferred only
- 17beta-hydroxy-androst-5-en-3-one is a substrate of HSD3B1ProteinRhea RHEA:56936Inferred only
Reactions
2 reactions
androst-5-en-3beta,17beta-diol+NAD(1-)17beta-hydroxy-androst-5-en-3-one+NADH(2-)+hydron
Catalysed by HSD3B1
Reaction pageDirection not assertedBalanced
Rhea RHEA:56932CC BY 4.0Reference data
17beta-hydroxy-androst-5-en-3-onetestosterone
Catalysed by HSD3B1
Reaction pageDirection not assertedBalanced
Rhea RHEA:56936CC BY 4.0Reference data