Compound
2-hydroxytestosterone
An androstanoid that is testosterone substituted at C2 by a hydroxy group with undefined stereochemistry.
Definition from ChEBI (CHEBI:86013), read 2026-09-23. CC BY 4.0.
CHEBI:86013ChEBI
Structure
- Class
- Organic compound
- Formula
- C19H28O3
- Mass
- 304.43 g/mol
- Charge
- 0
- InChIKey
- ZOIPFFUVGMVQGE-GBMNOFRWSA-N
- SMILES
- [H][C@@]12CCC3=CC(=O)C(O)C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Chemical structure
- 2-hydroxytestosterone has the functional parent testosteroneCompoundChEBI CHEBI:86013Inferred only
Statements
1 statement
1 statement · 1 reference database · Subject: 2-hydroxytestosterone · Sources: Rhea
- 2-hydroxytestosterone is metabolised by CYP46A1ProteinRhea RHEA:46300Inferred only
Reactions
1 reaction
testosterone+reduced [NADPH--hemoprotein reductase]+dioxygen2-hydroxytestosterone+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP46A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:46300CC BY 4.0Reference data
Other names
4 names
Resolves to: 2-hydroxytestosterone
- Also called
- (17beta)-2,17-dihydroxyandrost-4-en-3-one(17β)-2,17-dihydroxyandrost-4-en-3-one
- Systematic name
- 2,17beta-dihydroxyandrost-4-en-3-one2,17β-dihydroxyandrost-4-en-3-one