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Proteins/UNIPROT:Q8WVQ1
Calcium-dependent nucleotidase with a preference for ribonucleosides diphosphate UDP, GDP and IDP, while having very low activity towards ADP and CDP. In vitro, it can also act with low or negligible efficiency on ribonucletides triphosphate UTP, GTP, ITP, ATP and CTP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis..
Function from UniProtKB (Q8WVQ1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
539 statements
539 statements · 7 reference databases · Subject: CANT1 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways · Rows fetched: 300
8 reactions
ADP+waterAMP+proton+phosphate(3-)
Catalysed by ENTPD2 or ENTPD1 or ENTPD3 or CANT1 or ENTPD5 or ENTPD8 or ENTPD6
Reaction pageLeft to rightBalancedEC 3.6.1.5, 3.6.1.6cytosol
Human-GEM MAR03998CC BY 4.0Reference data
5 names
Resolves to: CANT1
Reaction pageLeft to rightBalancedEC 3.6.1.5, 3.6.1.6endoplasmic reticulum
Human-GEM MAR04059CC BY 4.0Reference data
water+UDPproton+phosphate(3-)+UMP
Catalysed by ENTPD2 or ENTPD1 or ENTPD3 or CANT1 or ENTPD5 or ENTPD8 or ENTPD4 or ENTPD6
Reaction pageLeft to rightBalancedEC 3.6.1.5, 3.6.1.6extracellular space
Human-GEM MAR04060CC BY 4.0Reference data
GDP+waterGMP+proton+phosphate(3-)
Catalysed by ENTPD2 or ENTPD1 or ENTPD3 or CANT1 or ENTPD5 or ENTPD8 or ENTPD4 or ENTPD6
Reaction pageLeft to rightBalancedEC 3.6.1.5, 3.6.1.6, 3.6.1.42extracellular space
Human-GEM MAR04134CC BY 4.0Reference data
GTP+waterGDP+proton+phosphate(3-)
Catalysed by ENTPD2 or DNM2 or DNM1L or DNM1 or ENTPD1 or EFL1 or EEF1A1 or GFM2 or EEF2 or ENTPD3 or GFM1 or CANT1 and 5 more alternatives
Reaction pageLeft to rightBalancedEC 3.6.5.1, 3.6.5.2, 3.6.5.3, 3.6.5.4, 3.6.5.5, 3.6.5.6extracellular space
Human-GEM MAR04136CC BY 4.0Reference data
water+CHEBI:17808proton+CHEBI:17202+phosphate(3-)
Catalysed by ENTPD2 or ENTPD1 or ENTPD3 or CANT1 or ENTPD5 or ENTPD8 or ENTPD4 or ENTPD6
Reaction pageLeft to rightBalancedEC 3.6.1.5, 3.6.1.6extracellular space
Human-GEM MAR04342CC BY 4.0Reference data
water+UDPproton+phosphate(3-)+UMP
Catalysed by CANT1 or ENTPD4 or ENTPD6
Reaction pageLeft to rightBalancedEC 3.6.1.6Golgi apparatus
Human-GEM MAR08485CC BY 4.0Reference data
a ribonucleoside 5'-diphosphate+waterCHEBI:58043+hydrogenphosphate+hydron
Catalysed by ENTPD6 or ENTPD3 or ENTPD5 or ENTPD1 or ENTPD8 or CANT1 or ENTPD4 or ENTPD2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36799CC BY 4.0Reference data