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Proteins/UNIPROT:Q92947
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive..
Function from UniProtKB (Q92947), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
94 statements
94 statements · 8 reference databases · Subject: GCDH · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
FAD+glutaryl-CoA+protoncarbon dioxide+(2E)-butenoyl-CoA+FADH2
Catalysed by GCDH
Reaction pageLeft to rightBalancedEC 1.3.8.6mitochondrial matrix
Human-GEM MAR04243CC BY 4.0Reference data
glutaryl-CoA+oxidized [electron-transfer flavoprotein]+2hydron(2E)-butenoyl-CoA+reduced [electron-transfer flavoprotein]
1 name
Resolves to: GCDH
Catalysed by GCDH
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13389CC BY 4.0Reference data