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Proteins/UNIPROT:P13639
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome..
Function from UniProtKB (P13639), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
68 statements
68 statements · 4 reference databases · Subject: EEF2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 reactions
2 names
Resolves to: EEF2
Human-GEM MAR04136CC BY 4.0Reference data
GTP+waterGDP+hydrogenphosphate+hydron
Catalysed by IRGM or RAB19 or TUBAL3 or GTPBP1 or RAB27B or RHOD or DNM1L or MRAS or RAB29 or OPA1 or EIF5B or ENTPD3 and 183 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:19669CC BY 4.0Reference data