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Proteins/UNIPROT:P20823
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity)..
(Microbial infection) Plays a crucial role for hepatitis B virus gene transcription and DNA replication. Mechanistically, synergistically cooperates with NR5A2 to up-regulate the activity of one of the critical cis-elements in the hepatitis B virus genome enhancer II (ENII)..
Function from UniProtKB (P20823), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
6 rows
98 statements
98 statements · 4 reference databases · Subject: HNF1A · Sources: gene ontology, Hetionet, Reactome, WikiPathways
7 names
Resolves to: HNF1A