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Proteins/UNIPROT:Q9UJP4
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome..
Function from UniProtKB (Q9UJP4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
697 statements
697 statements · 3 reference databases · Subject: KLHL21 · Sources: gene ontology, Hetionet, Reactome · Rows fetched: 300
2 names
Resolves to: KLHL21