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Proteins/UNIPROT:Q5T447
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity)..
Function from UniProtKB (Q5T447), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
83 statements
83 statements · 2 reference databases · Subject: HECTD3 · Sources: Hetionet, Reactome
1 reaction
2 names
Resolves to: HECTD3
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data