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Proteins/UNIPROT:P35548
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter..
Function from UniProtKB (P35548), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
64 statements
64 statements · 4 reference databases · Subject: MSX2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: MSX2