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Proteins/UNIPROT:Q969S9
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation..
Function from UniProtKB (Q969S9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
6 statements
6 statements · 2 reference databases · Subject: GFM2 · Sources: Hetionet, Reactome
2 reactions
7 names
Resolves to: GFM2
Human-GEM MAR04136CC BY 4.0Reference data
GTP+waterGDP+hydrogenphosphate+hydron
Catalysed by IRGM or RAB19 or TUBAL3 or GTPBP1 or RAB27B or RHOD or DNM1L or MRAS or RAB29 or OPA1 or EIF5B or ENTPD3 and 183 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:19669CC BY 4.0Reference data