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Proteins/UNIPROT:P32754
Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism. In addition may act as a N6-methyltransferase that methylates adenosine residues at the N(6) position of some RNAs..
Function from UniProtKB (P32754), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
218 statements
218 statements · 8 reference databases · Subject: HPD · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
dioxygen+3-phenylpyruvate(2-hydroxyphenyl)acetic acid+carbon dioxide
Catalysed by HPD
Reaction pageLeft to rightBalancedEC 1.13.11.27cytosol
Human-GEM MAR06726CC BY 4.0Reference data
3-(4-hydroxyphenyl)pyruvate+dioxygencarbon dioxide+homogentisate
Catalysed by HPD
Reaction pageLeft to rightBalancedEC 1.13.11.27cytosol
5 names
Resolves to: HPD
3-(4-hydroxyphenyl)pyruvate+dioxygenhomogentisate+carbon dioxide
Catalysed by HPD
Reaction pageLeft to rightBalanced
Rhea RHEA:16189CC BY 4.0Reference data
an adenosine in mRNA+S-adenosyl-L-methioninean N(6)-methyladenosine in mRNA+S-adenosyl-L-homocysteine+hydron
Catalysed by HPD or METTL3 or METTL16 or TMT1A
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55584CC BY 4.0Reference data