Proteins/UNIPROT:P55287

CDH11

ProteinUNIPROT:P55287

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration..

Function from UniProtKB (P55287), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

Elsahy-Waters syndrome has a germline basis in CDH11DiseaseGenCC HGNC:1750|MONDO:0008885Inferred only
Teebi hypertelorism syndrome 2 has a germline basis in CDH11DiseaseGenCC HGNC:1750|MONDO:0030674Inferred only

Statements

78 statements

78 statements · 4 reference databases · Subject: CDH11 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CDH11 interacts with ATF7IPProteinHetionet hetionet:interacts:1009-55729Inferred only
CDH2 interacts with CDH11ProteinHetionet hetionet:interacts:1000-1009Inferred only
CDH11 interacts with CRKProteinHetionet hetionet:interacts:1009-1398Inferred only
CDH11 interacts with CTNNB1ProteinHetionet hetionet:interacts:1009-1499Inferred only
CDH11 participates in Activation of STAT3 by cadherin engagementPathwayReactome R-HSA-9958825Inferred only
CDH11 participates in Adherens junctions interactionsPathwayReactome R-HSA-418990Inferred only
CDH11 participates in CDH11 homotypic and heterotypic interactionsPathwayReactome R-HSA-9833576Inferred only
CDH11 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
CDH11 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
CDH11 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
CDH11 participates in Hippo Merlin signaling dysregulationPathwayWikiPathways WP4541Inferred only
CDH11 participates in Hippo signaling regulationPathwayWikiPathways WP4540Inferred only

Show the remaining 66

CDH11 participates in Neural crest cell migration during developmentPathwayWikiPathways WP4564Inferred only
CDH11 participates in Neural crest cell migration in cancerPathwayWikiPathways WP4565Inferred only
CDH11 participates in Pleural mesotheliomaPathwayWikiPathways WP5087Inferred only
CDH11 participates in Regulation of CDH11 Expression and FunctionPathwayReactome R-HSA-9759475Inferred only
CDH11 participates in Regulation of CDH11 functionPathwayReactome R-HSA-9762292Inferred only
CDH11 participates in Regulation of CDH11 mRNA translation by microRNAsPathwayReactome R-HSA-9759811Inferred only
CDH11 participates in Regulation of Expression and Function of Type II Classical CadherinsPathwayReactome R-HSA-9764260Inferred only
CDH11 participates in Regulation of Homotypic Cell-Cell AdhesionPathwayReactome R-HSA-9759476Inferred only
CDH11 participates in SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)PathwayReactome R-HSA-9958810Inferred only
CDH11 regulates negative regulation of cell migrationBiological processgene ontology P55287|GO:0030336Inferred only
CDH11 decreases the expression of ACTN4ProteinHetionet hetionet:regulates:1009-81Inferred only
CDH11 decreases the expression of AMIGO2ProteinHetionet hetionet:regulates:1009-347902Inferred only
CDH11 decreases the expression of ATP1B1ProteinHetionet hetionet:regulates:1009-481Inferred only
CDH11 decreases the expression of BASP1ProteinHetionet hetionet:regulates:1009-10409Inferred only
CDH11 decreases the expression of CANT1ProteinHetionet hetionet:regulates:1009-124583Inferred only
CDH11 decreases the expression of CCNA2ProteinHetionet hetionet:regulates:1009-890Inferred only
CDH11 decreases the expression of CDC20ProteinHetionet hetionet:regulates:1009-991Inferred only
CDH11 decreases the expression of CDC25BProteinHetionet hetionet:regulates:1009-994Inferred only
CDH11 increases the expression of CES1ProteinHetionet hetionet:regulates:1009-1066Inferred only
CDH11 decreases the expression of CLSTN1ProteinHetionet hetionet:regulates:1009-22883Inferred only
CDH11 increases the expression of CPVLProteinHetionet hetionet:regulates:1009-54504Inferred only
CDH11 increases the expression of CRYZProteinHetionet hetionet:regulates:1009-1429Inferred only
CDH11 decreases the expression of CSRP1ProteinHetionet hetionet:regulates:1009-1465Inferred only
CDH11 decreases the expression of CTSLProteinHetionet hetionet:regulates:1009-1514Inferred only
CDH11 increases the expression of EAPPProteinHetionet hetionet:regulates:1009-55837Inferred only
CDH11 decreases the expression of EIF4EBP1ProteinHetionet hetionet:regulates:1009-1978Inferred only
CDH11 decreases the expression of ERBB2ProteinHetionet hetionet:regulates:1009-2064Inferred only
CDH11 increases the expression of ERCC5ProteinHetionet hetionet:regulates:1009-2073Inferred only
CDH11 decreases the expression of FHL2ProteinHetionet hetionet:regulates:1009-2274Inferred only
CDH11 increases the expression of FOXO4ProteinHetionet hetionet:regulates:1009-4303Inferred only
CDH11 increases the expression of GAAProteinHetionet hetionet:regulates:1009-2548Inferred only
CDH11 decreases the expression of HSPD1ProteinHetionet hetionet:regulates:1009-3329Inferred only
CDH11 decreases the expression of IGFBP3ProteinHetionet hetionet:regulates:1009-3486Inferred only
CDH11 decreases the expression of ITGAEProteinHetionet hetionet:regulates:1009-3682Inferred only
CDH11 increases the expression of KDM5AProteinHetionet hetionet:regulates:1009-5927Inferred only
CDH11 decreases the expression of KRT8ProteinHetionet hetionet:regulates:1009-3856Inferred only
CDH11 decreases the expression of LGALS1ProteinHetionet hetionet:regulates:1009-3956Inferred only
CDH11 decreases the expression of LMNB2ProteinHetionet hetionet:regulates:1009-84823Inferred only
CDH11 increases the expression of MCOLN1ProteinHetionet hetionet:regulates:1009-57192Inferred only
CDH11 decreases the expression of MRPL12ProteinHetionet hetionet:regulates:1009-6182Inferred only
CDH11 decreases the expression of NUP62ProteinHetionet hetionet:regulates:1009-23636Inferred only
CDH11 decreases the expression of PCNAProteinHetionet hetionet:regulates:1009-5111Inferred only
CDH11 decreases the expression of PLAGL2ProteinHetionet hetionet:regulates:1009-5326Inferred only
CDH11 decreases the expression of PUF60ProteinHetionet hetionet:regulates:1009-22827Inferred only
CDH11 increases the expression of RBKSProteinHetionet hetionet:regulates:1009-64080Inferred only
CDH11 decreases the expression of RND3ProteinHetionet hetionet:regulates:1009-390Inferred only
CDH11 decreases the expression of RRM2ProteinHetionet hetionet:regulates:1009-6241Inferred only
CDH11 increases the expression of RRP8ProteinHetionet hetionet:regulates:1009-23378Inferred only
CDH11 decreases the expression of S100A6ProteinHetionet hetionet:regulates:1009-6277Inferred only
CDH11 increases the expression of SATB1ProteinHetionet hetionet:regulates:1009-6304Inferred only
CDH11 decreases the expression of SGK1ProteinHetionet hetionet:regulates:1009-6446Inferred only
CDH11 decreases the expression of SLC5A6ProteinHetionet hetionet:regulates:1009-8884Inferred only
CDH11 decreases the expression of SNRPAProteinHetionet hetionet:regulates:1009-6626Inferred only
CDH11 increases the expression of SQORProteinHetionet hetionet:regulates:1009-58472Inferred only
CDH11 increases the expression of STK10ProteinHetionet hetionet:regulates:1009-6793Inferred only
CDH11 increases the expression of STXBP1ProteinHetionet hetionet:regulates:1009-6812Inferred only
CDH11 decreases the expression of TATDN2ProteinHetionet hetionet:regulates:1009-9797Inferred only
CDH11 decreases the expression of TFF1ProteinHetionet hetionet:regulates:1009-7031Inferred only
CDH11 decreases the expression of TMEM109ProteinHetionet hetionet:regulates:1009-79073Inferred only
CDH11 decreases the expression of TMEM50AProteinHetionet hetionet:regulates:1009-23585Inferred only
CDH11 decreases the expression of TRMT5ProteinHetionet hetionet:regulates:1009-57570Inferred only
CDH11 decreases the expression of TXLNAProteinHetionet hetionet:regulates:1009-200081Inferred only
CDH11 increases the expression of VAPBProteinHetionet hetionet:regulates:1009-9217Inferred only
CDH11 decreases the expression of VIMProteinHetionet hetionet:regulates:1009-7431Inferred only
CDH11 increases the expression of VPS26CProteinHetionet hetionet:regulates:1009-10311Inferred only
CDH11 increases the expression of WIF1ProteinHetionet hetionet:regulates:1009-11197Inferred only

Other names

3 names

Resolves to: CDH11

Also called: OB-cadherinOSF-4Osteoblast cadherin

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