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Proteins/UNIPROT:P16401
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber (By similarity). Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers and promote formation of the H3K27me3 mark by the PRC2/EED-EZH2 complex. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity)..
Function from UniProtKB (P16401), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
70 statements
70 statements · 3 reference databases · Subject: H1-5 · Sources: gene ontology, Hetionet, Reactome
5 names
Resolves to: H1-5