Loading the page.
Proteins/UNIPROT:O14832
Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono-branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms). Does not hydroxylate long and very long straight chain acyl-CoAs or 2-methyl- and 4-methyl-branched acyl-CoAs..
Function from UniProtKB (O14832), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
179 statements
179 statements · 7 reference databases · Subject: PHYH · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt
19 reactions
2-oxoglutarate(2-)+dioxygen+phytanoyl-CoAcarbon dioxide+succinate(2-)+MAM03363x
Catalysed by PHYH
Reaction pageLeft to rightBalancedEC 1.14.11.18peroxisome
Human-GEM MAR03384CC BY 4.0Reference data
2-oxoglutarate(2-)+dioxygen+phytanoyl-CoAMAM00655x+carbon dioxide+succinate(2-)
3 names
Resolves to: PHYH
Catalysed by PHYH
Reaction pageLeft to rightBalancedEC 1.14.11.18peroxisome
Human-GEM MAR03484CC BY 4.0Reference data
water+NAD(+)+2,6,10,14-tetramethylpentadecanal2,6,10,14-tetramethylpentadecanoate+2proton+NADH(2-)
Catalysed by PHYH
Reaction pageLeft to rightBalancedEC 1.14.11.18peroxisome
Human-GEM MAR03488CC BY 4.0Reference data
phytanoyl-CoA+2-oxoglutarate(2-)+dioxygenCHEBI:57334+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:16065CC BY 4.0Reference data
CHEBI:83969+2-oxoglutarate(2-)+dioxygenCHEBI:58784+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:44000CC BY 4.0Reference data
hexadecanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyhexadecanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54596CC BY 4.0Reference data
octanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyoctanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54600CC BY 4.0Reference data
decanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxydecanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54604CC BY 4.0Reference data
isovaleryl-CoA+2-oxoglutarate(2-)+dioxygenCHEBI:138296+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54612CC BY 4.0Reference data
heptadecanoyl-CoA+2-oxoglutarate(2-)+dioxygenCHEBI:138297+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54616CC BY 4.0Reference data
eicosanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyeicosanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54620CC BY 4.0Reference data
octadecanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyoctadecanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54624CC BY 4.0Reference data