Compound

3-oxodocosanoyl-CoA

A 3-oxo-fatty acyl-CoA arising from deprotonation of the phosphate and diphosphate functions of 3-oxodocosanoyl-CoA; principal microspecies at pH 7.3.

Definition from ChEBI (CHEBI:71451), read 2026-09-23. CC BY 4.0.

CHEBI:71451ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C43H72N7O18P3S
Mass: 1100.069 g/mol
Charge: -4
InChIKey: RKCOGGUHKPTOQJ-GNSUAQHMSA-J
SMILES: CCCCCCCCCCCCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: 3-oxodocosanoyl-CoA · Sources: Human-GEM, Rhea

Order

3-oxodocosanoyl-CoA is converted to eicosanoyl-CoACompoundRhea RHEA:78583Inferred only
eicosanoyl-CoA is converted to 3-oxodocosanoyl-CoACompoundRhea RHEA:35327Inferred only
eicosanoyl-CoA is converted to 3-oxodocosanoyl-CoACompoundRhea RHEA:78583Inferred only
3-oxodocosanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03069Inferred only
3-oxodocosanoyl-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03110Inferred only
3-oxodocosanoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03110Inferred only
3-oxodocosanoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR03110Inferred only
3-oxodocosanoyl-CoA is a substrate of HSD17B12ProteinHuman-GEM MAR02208Inferred only
3-oxodocosanoyl-CoA is a substrate of MYO5BProteinHuman-GEM MAR03069Inferred only

Reactions

14 reactions

eicosanoyl-CoA+proton+malonyl-CoA3-oxodocosanoyl-CoA+carbon dioxide+CHEBI:1146900
Catalysed by ELOVL5 or ELOVL1 or ELOVL4 or ELOVL3 or ELOVL7 or ELOVL6 or ELOVL2
Reaction pageLeft to rightBalancedEC 2.3.1.199cytosol
Human-GEM MAR02205CC BY 4.0Reference data
3-oxodocosanoyl-CoA+proton+NADPH(4-)MAM00776c+NADP(3-)
Catalysed by HSD17B12
Reaction pageLeft to rightBalancedEC 1.1.1.330cytosol
Human-GEM MAR02208CC BY 4.0Reference data
eicosanoyl-CoA+proton+malonyl-CoA3-oxodocosanoyl-CoA+carbon dioxide+CHEBI:1146900
Catalysed by LOXL2
Reaction pageLeft to rightBalancedEC 1.4.3.13extracellular space
Human-GEM MAR02494CC BY 4.0Reference data
MAM00776x+NAD(+)3-oxodocosanoyl-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03068CC BY 4.0Reference data
3-oxodocosanoyl-CoA+CHEBI:1146900CHEBI:15351+eicosanoyl-CoA
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03069CC BY 4.0Reference data
MAM00776m+NAD(+)3-oxodocosanoyl-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211mitochondrial matrix
Human-GEM MAR03109CC BY 4.0Reference data
3-oxodocosanoyl-CoA+CHEBI:1146900CHEBI:15351+eicosanoyl-CoA
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211mitochondrial matrix
Human-GEM MAR03110CC BY 4.0Reference data
3-oxodocosanoyl-CoA
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR04258CC BY 4.0Reference data
eicosanoyl-CoA+malonyl-CoA+hydron3-oxodocosanoyl-CoA+carbon dioxide+coenzyme A(4-)
Catalysed by ELOVL7 or ELOVL1 or ELOVL3
Reaction pageLeft to rightBalanced
Rhea RHEA:35327CC BY 4.0Reference data
CHEBI:71456+NADP(3-)3-oxodocosanoyl-CoA+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:35343CC BY 4.0Reference data
3-oxodocosanoyl-CoA+NADPH(4-)+hydronCHEBI:76375+NADP(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:39183CC BY 4.0Reference data
CHEBI:76375+NAD(1-)3-oxodocosanoyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:78579CC BY 4.0Reference data

Show the remaining 2

Other names

8 names

Resolves to: 3-oxodocosanoyl-CoA

Also called: 3-ketodocosanoyl-CoA(4-)3-ketodocosanoyl-CoA(4−)3-ketodocosanoyl-coenzyme A(4-)3-ketodocosanoyl-coenzyme A(4−)3-oxobehenoyl-CoA3-oxodocosanoyl-coenzyme A(4-)3-oxodocosanoyl-coenzyme A(4−)
Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-({2-[(3-oxodocosanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}butyl] diphosphate}