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Proteins/UNIPROT:P23786
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters..
Function from UniProtKB (P23786), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
4 rows
275 statements
275 statements · 7 reference databases · Subject: CPT2 · Sources: gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
79 reactions
CHEBI:1146900+MAM02117m(2E)-hexadecenoyl-CoA+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR00104CC BY 4.0Reference data
CHEBI:1146900+MAM02639m(S)-carnitine+oleoyl-CoA
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
3 names
Resolves to: CPT2
CHEBI:1146900+MAM02635mbutanoyl-CoA+(S)-carnitine
Reaction pageReversibleBalancedEC 2.3.1.7mitochondrial matrix
Human-GEM MAR00161CC BY 4.0Reference data
MAM00126m+CHEBI:1146900(2E)-octadecenoyl-CoA+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.6.1.1mitochondrial matrix
Human-GEM MAR00455CC BY 4.0Reference data
CHEBI:1146900+MAM02109mhexacosanoyl-CoA+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR01439CC BY 4.0Reference data
CHEBI:1146900+MAM02970m(S)-carnitine+tetracosanoyl-CoA
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR01481CC BY 4.0Reference data
CHEBI:1146900+MAM03727m(S)-carnitine+(9Z,12Z,15Z)-octadecatrienoyl-CoA
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR01489CC BY 4.0Reference data
MAM00024m+CHEBI:1146900(15Z)-tetracosenoyl-CoA+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.1.1.28mitochondrial matrix
Human-GEM MAR01556CC BY 4.0Reference data
MAM00133m+CHEBI:1146900(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR01736CC BY 4.0Reference data
MAM00109m+CHEBI:1146900MAM00110m+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 2.3.1.21mitochondrial matrix
Human-GEM MAR01757CC BY 4.0Reference data
MAM00130m+CHEBI:1146900MAM00131m+(S)-carnitine
Catalysed by CPT2
Reaction pageReversibleBalancedEC 3.6.1.15mitochondrial matrix
Human-GEM MAR01773CC BY 4.0Reference data
(S)-carnitine+palmitoyl-CoACHEBI:1146900+O-hexadecanoyl-(R)-carnitine
Reaction pageReversibleBalancedEC 2.3.1.21peroxisome
Human-GEM MAR02121CC BY 4.0Reference data