Compound
eicosanoate
A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of icosanoic acid (arachidic acid).
Definition from ChEBI (CHEBI:32360), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C20H39O2
- Mass
- 311.53 g/mol
- Charge
- -1
- InChIKey
- VKOBVWXKNCXXDE-UHFFFAOYSA-M
- SMILES
- CCCCCCCCCCCCCCCCCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
23 entities
23 entities reached.
0 reported hops23 assembled from the scaffold
- CD36ProteinUNIPROT:P16671transported byInferred only164 paths77 endpoints
- FABP5ProteinUNIPROT:Q01469transported byInferred only101 paths93 endpoints
- ACSL3ProteinUNIPROT:O95573substrate ofInferred only87 paths29 endpoints
- ACSL1ProteinUNIPROT:P33121substrate ofInferred only66 paths33 endpoints
- SLC27A3ProteinUNIPROT:Q5K4L6transported byInferred only48 paths24 endpoints
- ACSL4ProteinUNIPROT:O60488substrate ofInferred only46 paths23 endpoints
- SLC27A2ProteinUNIPROT:O14975substrate ofInferred only44 paths22 endpoints
- ACSL6ProteinUNIPROT:Q9UKU0substrate ofInferred only22 paths11 endpoints
- ACSL5ProteinUNIPROT:Q9ULC5substrate ofInferred only22 paths11 endpoints
- ACOT2ProteinUNIPROT:P49753substrate ofInferred only22 paths22 endpoints
- BAATProteinUNIPROT:Q14032substrate ofInferred only19 paths19 endpoints
- ACOT8ProteinUNIPROT:O14734substrate ofInferred only16 paths16 endpoints
Show the remaining 11
- SLC27A5ProteinUNIPROT:Q9Y2P5substrate ofInferred only15 paths15 endpoints
- ACSBG1ProteinUNIPROT:Q96GR2substrate ofInferred only14 paths7 endpoints
- ACSBG2ProteinUNIPROT:Q5FVE4substrate ofInferred only12 paths6 endpoints
- ACOT4ProteinUNIPROT:Q8N9L9substrate ofInferred only9 paths9 endpoints
- FABP3ProteinUNIPROT:P05413transported byInferred only9 paths9 endpoints
- SLC27A6ProteinUNIPROT:Q9Y2P4transported byInferred only8 paths4 endpoints
- ACOT7ProteinUNIPROT:O00154substrate ofInferred only6 paths6 endpoints
- FABP4ProteinUNIPROT:P15090transported byInferred only6 paths6 endpoints
- SLC27A4ProteinUNIPROT:Q6P1M0transported byInferred only4 paths2 endpoints
- FABP1ProteinUNIPROT:P07148transported byInferred only3 paths3 endpoints
- FABP2ProteinUNIPROT:P12104transported byInferred only1 path1 endpoint
What the reference databases state
Statements
44 statements
44 statements · 2 reference databases · Subject: eicosanoate · Sources: Human-GEM, Rhea
- eicosanoate is converted to eicosanoyl-CoACompoundRhea RHEA:46208Inferred only
- eicosanoyl-CoA is converted to eicosanoateCompoundRhea RHEA:40147Inferred only
- eicosanoate is a substrate of ACOT2ProteinHuman-GEM MAR02500Inferred only
- eicosanoate is a substrate of ACOT4ProteinHuman-GEM MAR02502Inferred only
- eicosanoate is a substrate of ACOT7ProteinHuman-GEM MAR02500Inferred only
- eicosanoate is a substrate of ACOT8ProteinHuman-GEM MAR02502Inferred only
- eicosanoate is a substrate of ACSBG1ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSBG1ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSBG2ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSBG2ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSL1ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSL1ProteinHuman-GEM MAR00283Inferred only
Show the remaining 32
- eicosanoate is a substrate of ACSL3ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSL3ProteinRhea RHEA:46208Inferred only
- eicosanoate is a substrate of ACSL3ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSL4ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSL4ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSL5ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSL5ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of ACSL6ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of ACSL6ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of BAATProteinHuman-GEM MAR02502Inferred only
- eicosanoate is a substrate of SLC27A2ProteinHuman-GEM MAR00283Inferred only
- eicosanoate is a substrate of SLC27A2ProteinHuman-GEM MAR02966Inferred only
- eicosanoate is a substrate of SLC27A5ProteinRhea RHEA:46208Inferred only
- eicosanoate is transported by CD36ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by CD36ProteinRhea RHEA:86483Inferred only
- eicosanoate is transported by FABP1ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP12ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP2ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP3ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP4ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP5ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP6ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP7ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by FABP9ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by SLC27A1ProteinHuman-GEM MAR08942Inferred only
- eicosanoate is transported by SLC27A1ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by SLC27A3ProteinHuman-GEM MAR08942Inferred only
- eicosanoate is transported by SLC27A3ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by SLC27A4ProteinHuman-GEM MAR08942Inferred only
- eicosanoate is transported by SLC27A4ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by SLC27A6ProteinHuman-GEM MAR00282Inferred only
- eicosanoate is transported by SLC27A6ProteinHuman-GEM MAR08942Inferred only
Reactions
36 reactions
fatty acid0.0001MAM00003e+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0082(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0001MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0041all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.002(8Z,11Z,14Z)-eicosatrienoate+0.0001(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.001(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0001MAM01932e+0.0001MAM02053e+0.0001dodecanoate+0.0001tetracosanoate+0.1535linoleic acid+0.0092alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0338tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.3837(9Z)-octadecenoate+0.0001MAM02648e+0.3015hexadecanoic acid+0.0522(9Z)-hexadecenoate+0.0001MAM02690e+0.0001MAM02745e+0.046octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00012CC BY 4.0Reference data
MAM02560e0.0048MAM00003e+0.0016(11Z,14Z)-eicosadienoate+0.0016MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0017(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0137(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0007docosanoate+0.0005hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0046all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0025(8Z,11Z,14Z)-eicosatrienoate+0.0019(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0011eicosanoate+0.0001elaidic acid+0.002(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932e+0.0001MAM02053e+0.0034dodecanoate+0.0012tetracosanoate+0.071linoleic acid+0.0005alpha-linolenic acid+0.0056MAM02456e+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0283tetradecanoate+0.0003(15Z)-tetracosenoate+0.0001MAM02613e+0.3746(9Z)-octadecenoate+0.0001MAM02648e+0.2949hexadecanoic acid+0.0686(9Z)-hexadecenoate+0.003MAM02690e+0.0001MAM02745e+0.1031octadecanoate+0.0001MAM02939e+0.0002tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00015CC BY 4.0Reference data
0.0001MAM00003e+0.0023(11Z,14Z)-eicosadienoate+0.0003MAM00010e+0.0002MAM00017e+0.003MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0004MAM00117e+0.0023MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0045MAM01197e+0.0002MAM01207e+0.001MAM01235e+0.0037MAM01238e+0.0008(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0051(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0002docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0046(11Z)-eicosenoate+0.0204MAM01585e+0.0012all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0021(8Z,11Z,14Z)-eicosatrienoate+0.0009(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0009eicosanoate+0.0001elaidic acid+0.0009(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0005MAM01932e+0.0001MAM02053e+0.0061dodecanoate+0.0001tetracosanoate+0.1573linoleic acid+0.0073alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.035tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.383(9Z)-octadecenoate+0.0004MAM02648e+0.2478hexadecanoic acid+0.0395(9Z)-hexadecenoate+0.0039MAM02690e+0.0001MAM02745e+0.0613octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoateMAM02561e
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00016CC BY 4.0Reference data
Transported by SLC27A6 or FABP3 or SLC27A1 or CD36 or SLC27A3 or FABP2 or FABP1 or FABP7 or FABP5 or SLC27A4 or FABP6 or FABP4 and 2 more alternatives
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR00282CC BY 4.0Reference data
ATP+CHEBI:1146900+eicosanoateAMP+eicosanoyl-CoA+diphosphate(3-)
Catalysed by ACSL4 or ACSBG1 or ACSL3 or ACSBG2 or SLC27A2 or ACSL1 or ACSL6 or ACSL5
Reaction pageLeft to rightBalancedEC 6.2.1.3cytosol
Human-GEM MAR00283CC BY 4.0Reference data
eicosanoyl-CoA+waterCHEBI:1146900+eicosanoate+proton
Catalysed by ACOT1 or BAAT or ACOT6
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00284CC BY 4.0Reference data
ATP+eicosanoate+waterADP+eicosanoate+proton+phosphate(3-)
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR00287CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR00567CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0001MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0024(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0208MAM01585c+0.0005all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0013(8Z,11Z,14Z)-eicosatrienoate+0.0017(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0013(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.0741linoleic acid+0.0037alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0096tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.122(9Z)-octadecenoate+0.0001MAM02648c+0.64hexadecanoic acid+0.0286(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.082octadecanoate+0.0028MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00685CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0016MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0032(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0521(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0217MAM01585c+0.0081all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0023(8Z,11Z,14Z)-eicosatrienoate+0.0018(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0003(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.003MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.281linoleic acid+0.0119alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0024tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4226(9Z)-octadecenoate+0.0001MAM02648c+0.12hexadecanoic acid+0.0229(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0384octadecanoate+0.0025MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00686CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0011MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0022(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0264(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0194MAM01585c+0.0221all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0141(8Z,11Z,14Z)-eicosatrienoate+0.0038(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0035(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0081MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.278linoleic acid+0.0023alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.003tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4519(9Z)-octadecenoate+0.0001MAM02648c+0.0849hexadecanoic acid+0.014(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0584octadecanoate+0.0026MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00687CC BY 4.0Reference data
fatty acid0.0005MAM00003c+0.0005(11Z,14Z)-eicosadienoate+0.0005MAM00010c+0.0005MAM00017c+0.0005MAM00019c+0.0005MAM00021c+0.0039MAM00094c+0.0005MAM00104c+0.0005MAM00111c+0.0005MAM00114c+0.0005MAM00115c+0.0005MAM00117c+0.0005MAM00128c+0.0005MAM00132c+0.0005MAM00135c+0.0005MAM00260c+0.0005MAM00265c+0.0005MAM00315c+0.0005MAM00341c+0.0005MAM01197c+0.0005MAM01207c+0.0005MAM01235c+0.0005MAM01238c+0.0011(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0709(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0005docosanoate+0.0005hexacosanoate+0.0005MAM01582c+0.0005MAM01583c+0.0005(11Z)-eicosenoate+0.0271MAM01585c+0.0252all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0228(8Z,11Z,14Z)-eicosatrienoate+0.0056(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0005eicosanoate+0.0005elaidic acid+0.0109(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0036MAM01932c+0.0005MAM02053c+0.0005dodecanoate+0.0005tetracosanoate+0.2479linoleic acid+0.0047alpha-linolenic acid+0.0005MAM02456c+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0054tetradecanoate+0.0005(15Z)-tetracosenoate+0.0005MAM02613c+0.1143(9Z)-octadecenoate+0.0178MAM02648c+0.2781hexadecanoic acid+0.0105(9Z)-hexadecenoate+0.0005MAM02690c+0.0005MAM02745c+0.1271octadecanoate+0.0026MAM02939c+0.0005tricosanoate+0.0005MAM03051c+0.0005(17Z)-hexacosenoate
Reaction pageReversibleBalance undeterminablecytosol
Human-GEM MAR00688CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 129 tissues, 171 transporter routes — routes, not measurements: transporters known to carry eicosanoate are expressed there, and no source reports it arriving.
Loading the model…
Other names
10 names
Resolves to: eicosanoate
- Also called
- (20:0)arachidatearachidinateCH3-[CH2]18-COO(-)CH3-[CH2]18-COO(-1)CH3‒[CH2]18‒COO-1CH3‒[CH2]18‒COO−eicosoaten-eicosanoate
- Systematic name
- icosanoate