eicosanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

355 compounds within 3 steps: 2 in 1, 39 in 2, 314 in 3

One step

fatty acidReach from here →
1. (10Z)-heptadecenoic acid formation
No catalyst recordedcytosolOne of 4 routes
eicosanoyl-CoAReach from here →
1. long-chain-fatty-acid-CoA ligase (eicosanoate)
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 4 morecytosolOne of 6 routes

Two steps

CHEBI:1146900Reach from here →
1. long-chain-fatty-acid-CoA ligase (eicosanoate)
2. Eicosanoyl-CoA hydrolase
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 7 morecytosolOne of 10 routes
2-hydroxyeicosanoyl-CoAReach from here →
1. long-chain-fatty-acid-CoA ligase (eicosanoate)
2. eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 5 more

Three steps

(S)-carnitineReach from here →
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 10 morecytosolOne of 260 routes
AReach from here →
Catalysed by

cytosol

hexadecanoic acidReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

linoleic acidReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

dodecanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

1-eicosanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol

docosanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

octadecanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

alpha-linolenic acidReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

elaidic acidReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

tetradecanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(9Z)-octadecenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

hexacosanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

tetracosanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

an N-acylsphinganineReach from here →

Catalysed by ASAH1, ACER2, ACER1, ASAH2 and 1 morecytosol

(9Z)-hexadecenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(15Z)-tetracosenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(11Z)-eicosenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

octadecanoyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, mitochondrial matrixOne of 2 routes

an acyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 4 morecytosol

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

N-eicosanoylsphinganineReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 7 morecytosol

3-oxodocosanoyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 11 morecytosolOne of 3 routes

(8Z,11Z,14Z)-eicosatrienoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

N-eicosanoyl-sphing-4-enineReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol

(2E)-eicosenoyl-CoAReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, peroxisomeOne of 4 routes

1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 5 morecytosol

eicosan-1-olReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol

(11Z,14Z)-eicosadienoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(17Z)-hexacosenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

(5Z,8Z,11Z)-eicosatrienoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

tricosanoateReach from here →

No catalyst recordedcytosol, extracellular spaceOne of 12 routes

1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholineReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 5 morecytosol

O-eicosanoyl-(R)-carnitineReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 5 morecytosol

N-eicosanoylglycinateReach from here →

Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 5 morecytosol

PTGS1

, PTGS2

cytosol, extracellular space

One of 11 routes

(14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →

Catalysed by CYP1A1, CYP1A2, CYP3A4, CYP2C8 and 4 morecytosol, extracellular space

(14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →

Catalysed by CYP1A1, CYP1A2, CYP3A4, CYP2C8 and 4 morecytosol, extracellular space

(11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by CYP2C8, CYP2C9, CYP2C19, CYP2J2 and 1 morecytosol, extracellular space

(11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by CYP1A1, CYP2C8, CYP2D6, CYP2C9 and 3 morecytosol, extracellular space

(8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by CYP2C9, CYP2J2cytosol, extracellular space

(8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by CYP1A1, CYP2D6, CYP2C9, CYP2C19 and 2 morecytosol, extracellular space

5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by CYP1A1, CYP1A2, CYP2E1, CYP3A4 and 22 morecytosol, extracellular spaceOne of 4 routes