folic acid

Three steps

• L-cystineReach from here →
  1. Folate Transport by Oats
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. L-cystine(out) + L-aspartate(in) = L-cystine(in) + L-aspartate(out)

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• 17beta-hydroxy-5alpha-androstan-3-oneReach from here →
  1. Folate Transport by Oats
  2. steroid sulfatase (5-alpha-dihydrotestosterone)
  3. steroid sulfatase (5-alpha-dihydrotestosterone)

  Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes

• iodideReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and iodide (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC26A4extracellular space, cytosol

• ubiquinonesReach from here →
  1. Folate Transport by Oats
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. succinate:quinone oxidoreductase

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SDHD and 3 moreextracellular space, cytosol, mitochondrial matrix

• L-valineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and valine (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 4 routes

• oxaloacetateReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. transport of malate and OAA (cytosol to mitochondria)

  Catalysed by SLC22A8, SLC22A7, SLC25A10extracellular space, cytosol, mitochondrial matrixOne of 11 routes

• L-arginineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of arginine and chloride (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 2 routes

• protein polypeptide chainReach from here →
  1. Folate Transport by Oats
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. PROTEIN_BS

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membrane

• pregnenoloneReach from here →
  1. Folate Transport by Oats
  2. Steryl-Sulfatase
  3. Pregnenolone-sulfate sulfohydrolase

  Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 4 routes

• 3-fumarylpyruvateReach from here →
  1. Folate Transport by Oats
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

  Catalysed by SLC22A8, SLC22A7, SLC25A10, FAHD1extracellular space, cytosol, mitochondrial matrix

• CHEBI:16857Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Threonine by Atb0 Transporter

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosol

• ferrocytochrome cReach from here →
  1. Folate Transport by Oats
  2. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)
  3. sulfite:ferricytochrome-c oxidoreductase

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane, mitochondrial matrix

• N-acetyl-L-aspartateReach from here →
  1. Folate Transport by Oats
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. acetyl-CoA:L-aspartate N-acetyltransferase

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• L-isoleucineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and isoleucine (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 2 routes

• CHEBI:17203Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Proline by the Apical Imino Amino Acid Transporters

  Catalysed by SLC22A8, SLC22A7, SLC26A6, CLTRN and 1 moreextracellular space, cytosolOne of 3 routes

• estroneReach from here →
  1. Folate Transport by Oats
  2. estrone 3-sulfate + H2O = estrone + sulfate + H(+)
  3. Estrone 3-sulfate sulfohydrolase

  Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes

• propanoateReach from here →
  1. Folate Transport by Oats
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. propanoate(out) + dehydroepiandrosterone 3-sulfate(in) = propanoate(in) + dehydroepiandrosterone 3-sulfate(out)

  Catalysed by SLC22A8, SLC22A7, STS, SLC22A9extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• enol-oxaloacetateReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. (S)-malate + a quinone = enol-oxaloacetate + a quinol

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SDHB and 1 moreextracellular space, cytosol, mitochondrial matrix

• L-cysteineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and cysteine (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 2 routes

• 3,3'-diiodo-L-thyronineReach from here →
  1. Folate Transport by Oats
  2. Steryl-Sulfatase
  3. Steryl-Sulfatase

  Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 3 routes

• glycine betaineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of betaine and chloride (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A12extracellular space, cytosolOne of 3 routes

• urateReach from here →
  1. Folate Transport by Oats
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)

  Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• CHEBI:17895Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Tyrosine by Atb0 Transporter

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 2 routes

• butanoateReach from here →
  1. Folate Transport by Oats
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. dehydroepiandrosterone 3-sulfate(in) + butanoate(out) = dehydroepiandrosterone 3-sulfate(out) + butanoate(in)

  Catalysed by SLC22A8, SLC22A7, STS, SLC22A9extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• CHEBI:18019Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and lysine (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosol

• thiocyanateReach from here →
  1. Folate Transport by Oats
  2. thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)
  3. thiosulfate:cyanide sulfurtranserase

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 4 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• 4-fumarylacetoacetateReach from here →
  1. Folate Transport by Oats
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)

  Catalysed by SLC22A8, SLC22A7, SLC25A10, FAHextracellular space, cytosol, mitochondrial matrix

• L-glutamineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of L-Glutamine by Atb0 Transporter

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 3 routes

• CHEBI:18095Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of trans-4-hydroxy-L-proline (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, CLTRN and 1 moreextracellular space, cytosol

• N-carbamoyl-beta-alanineReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of 3-Ureidopropionate

  Catalysed by SLC22A8, SLC22A7, SLC26A6extracellular space, cytosolOne of 2 routes

• hydrogen cyanideReach from here →
  1. Folate Transport by Oats
  2. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)
  3. thiosulfate:cyanide sulfurtranserase

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 2 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 2 routes

• 3-carboxy-4-methyl-5-propyl-2-furanpropanoateReach from here →
  1. Folate Transport by Oats
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)

  Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• L-sepiapterinReach from here →
  1. Folate Transport by Oats
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. L-sepiapterin(out) + a dicarboxylate(in) = L-sepiapterin(in) + a dicarboxylate(out)

  Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• (6R)-10-formyltetrahydrofolateReach from here →
  1. dihydrofolate:NAD+ oxidoreductase
  2. (6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH + H(+)
  3. (6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate

  Catalysed by DHFR, DHFR2, MTHFD1, MTHFD1Lcytosol

• (6R)-5,10-methylenetetrahydrofolic acidReach from here →
  1. dihydrofolate:NAD+ oxidoreductase
  2. 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase
  3. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase

  Catalysed by DHFR, DHFR2, SHMT1cytosolOne of 5 routes

• CHEBI:240943Reach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. 2-Methylbutyrylglycine Transport, Extracellular

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A5extracellular space, cytosolOne of 2 routes

• a quinolReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. (S)-malate + a quinone = enol-oxaloacetate + a quinol

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SDHB and 1 moreextracellular space, cytosol, mitochondrial matrix

• hypochlorous acidReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Peroxidase

  Catalysed by SLC22A8, SLC22A7, SLC26A6, LPOextracellular space, cytosolOne of 4 routes

• potassium atomReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC12A2 and 1 moreextracellular space, cytosolOne of 3 routes

• 3beta-hydroxyandrost-5-en-17-oneReach from here →
  1. Folate Transport by Oats
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. 3beta-Hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase

  Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes

• K(+)Reach from here →
  1. Folate Transport by Oats
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 5 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• Asp-tRNA(Asp)Reach from here →
  1. Folate Transport by Oats
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. L-Aspartate:tRNA(Asp) ligase (AMP-forming)

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane

• hydrogen sulfideReach from here →
  1. Folate Transport by Oats
  2. thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)
  3. 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)

  Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 2 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• formic acidReach from here →
  1. Folate Transport by Oats
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. transport of chloride and formate (cytosol to extracellular)

  Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC26A4extracellular space, cytosolOne of 2 routes

• citric acidReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. Citrate Transport, Mitochondrial

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SLC25A1extracellular space, cytosol, mitochondrial matrixOne of 10 routes

• (indol-3-yl)acetateReach from here →
  1. Folate Transport by Oats
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. (indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)

  Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• isocitric acidReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SLC25A1extracellular space, cytosol, mitochondrial matrixOne of 6 routes

• glutarateReach from here →
  1. Folate Transport by Oats
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. dehydroepiandrosterone 3-sulfate(out) + glutarate(in) = dehydroepiandrosterone 3-sulfate(in) + glutarate(out)

  Catalysed by SLC22A8, SLC22A7, STS, SLC22A24extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• pentanoateReach from here →
  1. Folate Transport by Oats
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. pentanoate(out) + dehydroepiandrosterone 3-sulfate(in) = pentanoate(in) + dehydroepiandrosterone 3-sulfate(out)

  Catalysed by SLC22A8, SLC22A7, STS, SLC22A9extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• cis-aconitic acidReach from here →
  1. Folate Transport by Oats
  2. transport of malate and sulfate (cytosol to mitochondria)
  3. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2

  Catalysed by SLC22A8, SLC22A7, SLC25A10, SLC25A1extracellular space, cytosol, mitochondrial matrixOne of 6 routes