glycine betaine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

471 compounds within 3 steps: 5 in 1, 65 in 2, 401 in 3

One step

(R)-carnitineReach from here →
1. glycine betaine(out) + (R)-carnitine(in) = glycine betaine(in) + (R)-carnitine(out)
Catalysed by SLC22A5inner side of the membrane, outer side of the membraneOne of 2 routes
CHEBI:17724Reach from here →
1. Trimethylaminoacetate:L-homosysteine S-methyltransferase
Catalysed by BHMT, BHMT2cytosol
chlorine(.)Reach from here →
1. transport of betaine and chloride (cytosol to extracellular)
Catalysed by SLC6A12extracellular space, cytosolOne of 3 routes
L-methionineReach from here →
1. Trimethylaminoacetate:L-homosysteine S-methyltransferase
Catalysed by BHMT, BHMT2cytosolOne of 2 routes
N,N-dimethylglycineReach from here →
1. L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine
Catalysed by BHMT

Two steps

(S)-carnitineReach from here →
1. transport of betaine and chloride (cytosol to extracellular)
2. Carnitine Transport by Atb0
Catalysed by SLC6A12, SLC6A14extracellular space, cytosol
CHEBI:1146900Reach from here →
1. Trimethylaminoacetate:L-homosysteine S-methyltransferase
2. N-acetylglutamate synthase (N-acetylmethionine)
Catalysed by BHMT, BHMT2, NAGScytosol, mitochondrial matrix
cholineReach from here →

Catalysed by SLC6A12, SLC5A7extracellular space, cytosol

L-leucineReach from here →

Catalysed by BHMT, BHMT2, SLC3A2, SLC7A5cytosol, extracellular spaceOne of 8 routes

CHEBI:15611Reach from here →

Catalysed by BHMT, BHMT2, PDPR, DMGDHcytosolOne of 3 routes

CHEBI:15699Reach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 3 routes

CHEBI:15971Reach from here →

Catalysed by BHMT, BHMT2, SLC7A6cytosol, extracellular spaceOne of 3 routes

sulfateReach from here →

Catalysed by SLC6A12, SLC26A6extracellular space, cytosol

L-citrullineReach from here →

Catalysed by BHMT, BHMT2, SLC7A6cytosol, extracellular spaceOne of 2 routes

iodideReach from here →

Catalysed by SLC6A12, SLC26A4extracellular space, cytosol

L-valineReach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 5 routes

L-arginineReach from here →

Catalysed by BHMT, BHMT2, SLC7A6cytosol, extracellular spaceOne of 7 routes

protein polypeptide chainReach from here →

Catalysed by BHMT, BHMT2cytosol

Met-tRNA(Met)Reach from here →

Catalysed by BHMT, BHMT2, MARS1cytosol

4-methylsulfanyl-2-oxobutanoateReach from here →

Catalysed by BHMT, BHMT2, AADATcytosol

formaldehydeReach from here →

Catalysed by BHMT, BHMT2, PDPR, DMGDHcytosolOne of 2 routes

CHEBI:16857Reach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 4 routes

oxalic acidReach from here →

Catalysed by SLC6A12, SLC26A6extracellular space, cytosol

L-isoleucineReach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 5 routes

CHEBI:17203Reach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 5 routes

O-hexadecanoyl-(R)-carnitineReach from here →

Catalysed by SLC22A5, CPT2, CPT1A, CPT1Binner side of the membrane, outer side of the membraneOne of 3 routes

AH2Reach from here →

Catalysed by BHMT, BHMT2, CDKAL1cytosolOne of 3 routes

L-cysteineReach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 8 routes

CHEBI:17895Reach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 6 routes

CHEBI:18019Reach from here →

Catalysed by BHMT, BHMT2, SLC7A6cytosol, extracellular spaceOne of 3 routes

L-glutamineReach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 7 routes

CHEBI:18095Reach from here →

Catalysed by SLC6A12, CLTRN, SLC6A20extracellular space, cytosol

O-octanoyl-(R)-carnitineReach from here →

Catalysed by SLC22A5, CPT2, CRAT, CROTinner side of the membrane, outer side of the membraneOne of 3 routes

N-carbamoyl-beta-alanineReach from here →

Catalysed by SLC6A12extracellular space, cytosolOne of 2 routes

S-methylmercury-L-cysteineReach from here →

Catalysed by BHMT, BHMT2, SLC7A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

O-butanoyl-(R)-carnitineReach from here →

Catalysed by SLC22A5, CRATinner side of the membrane, outer side of the membrane

CHEBI:240943Reach from here →

Catalysed by SLC6A12, SLC6A5extracellular space, cytosolOne of 2 routes

hypochlorous acidReach from here →

Catalysed by SLC6A12, LPOextracellular space, cytosolOne of 4 routes

potassium atomReach from here →

Catalysed by SLC6A12, SLC12A2, SLC12A1extracellular space, cytosolOne of 2 routes

O-decanoyl-(R)-carnitineReach from here →

Catalysed by SLC22A5, CPT2, CRATinner side of the membrane, outer side of the membrane

L-aspartateReach from here →

Catalysed by BHMT, BHMT2, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

formic acidReach from here →

Catalysed by SLC6A12, SLC26A4extracellular space, cytosolOne of 2 routes

malonic acidReach from here →

Catalysed by SLC6A12extracellular space, cytosolOne of 2 routes

glutarateReach from here →

Catalysed by SLC22A5, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

4-methylthio-2-oxobutanoic acidReach from here →

Catalysed by BHMT, BHMT2, IL4I1cytosol

L-ornithineReach from here →

Catalysed by BHMT, BHMT2, SLC7A6cytosol, extracellular spaceOne of 2 routes

taurineReach from here →

Catalysed by SLC6A12, SLC6A6extracellular space, cytosolOne of 2 routes

O-propanoyl-(R)-carnitineReach from here →

Catalysed by SLC22A5, CRATinner side of the membrane, outer side of the membraneOne of 3 routes

glycineReach from here →

Catalysed by BHMT, BHMT2, SLC7A5cytosol, extracellular spaceOne of 8 routes

sarcosineReach from here →

Catalysed by BHMT, DMGDH