N-acetyl-L-aspartate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

381 compounds within 3 steps: 4 in 1, 48 in 2, 329 in 3

One step

L-aspartateReach from here →
1. N-Acetyl-L-aspartate amidohydrolase
Catalysed by ASPA, ACY3cytosolOne of 2 routes
acetateReach from here →
1. N-Acetyl-L-aspartate amidohydrolase
Catalysed by ASPA, ACY3cytosolOne of 2 routes
N-acetyl-L-aspartyl-L-glutamateReach from here →
1. N-acetyl-L-aspartate + L-glutamate + ATP = N-acetyl-L-aspartyl-L-glutamate + ADP + phosphate + H(+)
Catalysed by RIMKLA, RIMKLB
N-acetyl-L-aspartyl-L-glutamyl-L-glutamateReach from here →
1. N-acetyl-L-aspartate + 2 L-glutamate + 2 ATP = N-acetyl-L-aspartyl-L-glutamyl-L-glutamate + 2 ADP + 2 phosphate + 2 H(+)
Catalysed by RIMKLA

Two steps

CHEBI:1146900Reach from here →
1. N-Acetyl-L-aspartate amidohydrolase
2. acetyl-CoA:L-aspartate N-acetyltransferase
Catalysed by ASPA, ACY3, NAT8Lcytosol, mitochondrial matrix
2-hydroxybutyric acidReach from here →
1. N-Acetyl-L-aspartate amidohydrolase
2. transport of 2-hydroxybutyrate and acetate (cytosol to extracellular)
Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 2 morecytosol, extracellular spaceOne of 2 routes

N-acetylcadaverineReach from here →

Catalysed by ASPA, ACY3, HDAC10cytosol

acetoacetateReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

a phenyl acetateReach from here →

Catalysed by ASPA, ACY3, PON1, PON2 and 1 morecytosol

acetylpyruvateReach from here →

Catalysed by ASPA, ACY3, FAHD1cytosol

pyruvateReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinoic acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 1 morecytosol, extracellular spaceOne of 2 routes

L-leucineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

N-carbamoyl-L-aspartic acidReach from here →

Catalysed by ASPA, ACY3, CADcytosol

sulfateReach from here →

Catalysed by ASPA, ACY3, SLC25A14, SLC25A30cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-cystineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-valineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

oxaloacetateReach from here →

Catalysed by ASPA, ACY3, GOT2cytosol, mitochondrial matrixOne of 5 routes

protein polypeptide chainReach from here →

Catalysed by ASPA, ACY3cytosol

N(2)-acetyl-L-ornithineReach from here →

Catalysed by ASPA, ACY3, ACY1cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 2 morecytosol, extracellular spaceOne of 2 routes

CHEBI:17203Reach from here →

Catalysed by ASPA, ACY3cytosol, extracellular space

17alpha-hydroxyprogesteroneReach from here →

Catalysed by ASPA, ACY3, CYP17A1cytosol, endoplasmic reticulum

4-methylumbelliferyl acetateReach from here →

Catalysed by ASPA, ACY3, CES2, ESD and 1 morecytosol

L-glutamineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

potassium atomReach from here →

Catalysed by ASPA, ACY3, SLC1A7, SLC1A3 and 3 morecytosol, extracellular space

17alpha-hydroxypregnenoloneReach from here →

Catalysed by ASPA, ACY3, CYP17A1cytosol, endoplasmic reticulum

K(+)Reach from here →

Catalysed by ASPA, ACY3, SLC1A7, SLC1A3 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

Asp-tRNA(Asp)Reach from here →

Catalysed by ASPA, ACY3, DARS1cytosol

formic acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 1 morecytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 2 morecytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 2 morecytosol, extracellular spaceOne of 2 routes

N-carbamoyl-L-aspartateReach from here →

Catalysed by ASPA, ACY3, CADcytosol

(S)-lactic acidReach from here →

Catalysed by ASPA, ACY3, SLC16A4, SLC16A5 and 4 morecytosol, extracellular spaceOne of 2 routes

N-(acetyl)-sphing-4-enineReach from here →

Catalysed by ASPA, ACY3, ASAH1cytosol

2-(N(omega)-L-arginino)succinateReach from here →

Catalysed by ASPA, ACY3, ASS1cytosolOne of 2 routes

N-acetyl-D-glucosamine 6-phosphateReach from here →

Catalysed by ASPA, ACY3, AMDHD2cytosol

N(6)-(1,2-dicarboxyethyl)-AMPReach from here →

Catalysed by ASPA, ACY3, ADSS2, ADSS1cytosolOne of 2 routes

L-methionineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-tryptophanReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

beta-alanineReach from here →

Catalysed by ASPA, ACY3, GAD2cytosolOne of 2 routes

L-alanineReach from here →

Catalysed by ASPA, ACY3, AGXT2cytosol

L-asparagineReach from here →

Catalysed by ASPA, ACY3, ASNScytosolOne of 2 routes

N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagineReach from here →

Catalysed by ASPA, ACY3, AGAcytosol

L-phenylalanineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

N-acetylputrescineReach from here →

Catalysed by ASPA, ACY3, HDAC10cytosol

L-tyrosineReach from here →

Catalysed by ASPA, ACY3, SLC7A13cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

N(omega),N(omega)-dimethyl-L-arginineReach from here →

Catalysed by ASPA, ACY3, AGXT2cytosol

(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateReach from here →

Catalysed by ASPA, ACY3, PAICScytosolOne of 2 routes

N(8)-acetylspermidineReach from here →

Catalysed by ASPA, ACY3, HDAC10cytosol