Compound
thiocyanate
A pseudohalide anion obtained by deprotonation of the thiol group of thiocyanic acid.
Definition from ChEBI (CHEBI:18022), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Inorganic compound, anion
- Formula
- CNS
- Mass
- 58.085 g/mol
- Charge
- -1
- InChIKey
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M
- SMILES
- N#C[S-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
14 entities
14 entities reached.
0 reported hops14 assembled from the scaffold
- CLIC4ProteinUNIPROT:Q9Y696transported byInferred only135 paths133 endpoints
- CLIC1ProteinUNIPROT:O00299transported byInferred only130 paths115 endpoints
- SLC1A5ProteinUNIPROT:Q15758transported byInferred only45 paths44 endpoints
- SLC1A4ProteinUNIPROT:P43007transported byInferred only32 paths32 endpoints
- MPOProteinUNIPROT:P05164substrate ofInferred only26 paths13 endpoints
- LPOProteinUNIPROT:P22079substrate ofInferred only15 paths5 endpoints
- PRDX6ProteinUNIPROT:P30041substrate ofInferred only15 paths15 endpoints
- TSTProteinUNIPROT:Q16762substrate ofInferred only14 paths7 endpoints
- MPSTProteinUNIPROT:P25325substrate ofInferred only8 paths8 endpoints
- EPXProteinUNIPROT:P11678substrate ofInferred only6 paths3 endpoints
- SLC5A5ProteinUNIPROT:Q92911transported byInferred only4 paths4 endpoints
- CLDN17ProteinUNIPROT:P56750transported byInferred only4 paths4 endpoints
What the reference databases state
Statements
27 statements
27 statements · 2 reference databases · Subject: thiocyanate · Sources: Human-GEM, Rhea
- thiocyanate is converted to hypothiocyanous acidCompoundRhea RHEA:69416Inferred only
- hypothiocyanous acid is converted to thiocyanateCompoundHuman-GEM MAR06523Inferred only
- thiocyanate is converted to hypothiocyanous acidCompoundHuman-GEM MAR06523Inferred only
- thiocyanate is converted to hypothiocyanous acidCompoundHuman-GEM MAR02531Inferred only
- thiocyanate is converted to hypothiocyanous acidCompoundHuman-GEM MAR02529Inferred only
- hypothiocyanous acid is converted to thiocyanateCompoundHuman-GEM MAR02529Inferred only
- hypothiocyanous acid is converted to thiocyanateCompoundHuman-GEM MAR02531Inferred only
- thiocyanate is a substrate of EPXProteinHuman-GEM MAR06523Inferred only
- thiocyanate is a substrate of EPXProteinRhea RHEA:69416Inferred only
- thiocyanate is a substrate of LPOProteinHuman-GEM MAR02529Inferred only
- thiocyanate is a substrate of LPOProteinHuman-GEM MAR06523Inferred only
- thiocyanate is a substrate of LPOProteinRhea RHEA:69416Inferred only
Show the remaining 15
- thiocyanate is a substrate of MPOProteinHuman-GEM MAR02531Inferred only
- thiocyanate is a substrate of MPOProteinRhea RHEA:69416Inferred only
- thiocyanate is a substrate of MPSTProteinHuman-GEM MAR06520Inferred only
- thiocyanate is a substrate of PRDX6ProteinHuman-GEM MAR02531Inferred only
- thiocyanate is a substrate of TSTProteinHuman-GEM MAR06520Inferred only
- thiocyanate is a substrate of TSTProteinRhea RHEA:16881Inferred only
- thiocyanate is transported by CLCN1ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by CLCN2ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by CLDN17ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by CLIC1ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by CLIC4ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by SLC1A4ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by SLC1A5ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by SLC26A7ProteinRhea RHEA:75347Inferred only
- thiocyanate is transported by SLC5A5ProteinRhea RHEA:71215Inferred only
Reactions
15 reactions
proton+hydrogen peroxide+thiocyanatewater+hypothiocyanous acid
Catalysed by LPO
Reaction pageReversibleBalancedEC 1.8.1.4extracellular space
Human-GEM MAR02529CC BY 4.0Reference data
proton+hydrogen peroxide+thiocyanatewater+hypothiocyanous acid
Reaction pageReversibleBalancedEC 1.8.1.4lysosome
Human-GEM MAR02531CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06514CC BY 4.0Reference data
hydrogen cyanide+2-oxo-3-sulfanylpropanoateproton+pyruvate+thiocyanate
Reaction pageLeft to rightBalancedEC 2.8.1.2cytosol
Human-GEM MAR06518CC BY 4.0Reference data
hydrogen cyanide+thiosulfateproton+sulfite+thiocyanate
Reaction pageReversibleBalancedEC 2.8.1.1mitochondrial matrix
Human-GEM MAR06520CC BY 4.0Reference data
proton+hydrogen peroxide+thiocyanatewater+hypothiocyanous acid
Reaction pageReversibleBalancedEC 1.11.1.7, 1.2.4.4, 1.8.1.4cytosol
Human-GEM MAR06523CC BY 4.0Reference data
Reaction pageLeft to rightBalancedmitochondrial matrix, cytosol
Human-GEM MAR08848CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09420CC BY 4.0Reference data
thiosulfate+hydrogen cyanidethiocyanate+sulfite+2hydron
Catalysed by TST
Reaction pageDirection not assertedBalanced
Rhea RHEA:16881CC BY 4.0Reference data
thiocyanate+water+2hydronCHEBI:16573+ammonium
Reaction pageDirection not assertedBalanced
Rhea RHEA:21464CC BY 4.0Reference data
thiocyanate+S-adenosyl-L-methionineCHEBI:61112+S-adenosyl-L-homocysteine
Reaction pageDirection not assertedBalanced
Rhea RHEA:28014CC BY 4.0Reference data
thiocyanate+2Fe(III)-[cytochrome c]+waterCHEBI:29195+CHEBI:26833+2Fe(II)-[cytochrome c]+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:63880CC BY 4.0Reference data
Where it reaches
10 systems, 28 regions, 185 tissues, 301 transporter routes — routes, not measurements: transporters known to carry thiocyanate are expressed there, and no source reports it arriving.
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Other names
18 names
Resolves to: thiocyanate
- Also called
- [S-C#N](-)[S‒C≡N]−N#C-S(-)N≡C‒S−NCS-RhodanidrhodanideSCN(-)SCN−THIOCYANATE IONthiocyanate ion (1-)thiocyanate ion (1−)Thiozyanat
- Systematic name
- nitridosulfidocarbonate(1-)nitridosulfidocarbonate(1−)nitridothiocarbonate(1-)nitridothiocarbonate(1−)nitridothiocarbonate(IV)