folic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

139 compounds within 3 steps: 2 in 1, 31 in 2, 106 in 3

One step

sulfateReach from here →
1. Folate Transport by Oats
Catalysed by SLC22A8, SLC22A7extracellular space, cytosolOne of 2 routes
7,8-dihydrofolateReach from here →
1. dihydrofolate:NAD+ oxidoreductase
Catalysed by DHFR, DHFR2cytosolOne of 3 routes

Two steps

pregnenolone sulfateReach from here →
1. Folate Transport by Oats
2. Steryl-Sulfatase
Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 2 routes
androsterone 3alpha-sulfateReach from here →
1. Folate Transport by Oats
2. steroid sulfatase (androsterone sulfate)
Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes

Three steps

(S)-carnitineReach from here →
Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosol
CHEBI:1146900Reach from here →
Catalysed by and 1 more

cholesterol sulfate

Reach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 2 routes

5alpha-dihydrotestosterone sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes

an aryl sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, ARSL, ARSF and 4 moreextracellular space, cytosol

(S)-malateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A10extracellular space, cytosol, mitochondrial matrixOne of 4 routes

malonateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

quinolinic acidReach from here →

Catalysed by SLC22A8, SLC22A7, SLC22A6extracellular space, cytosolOne of 2 routes

oxalic acidReach from here →

Catalysed by SLC22A8, SLC22A7, SLC26A6extracellular space, cytosol

sulfiteReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

3,3'-diiodo-L-thyronine sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 2 routes

fumaric acidReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A10extracellular space, cytosol, mitochondrial matrixOne of 2 routes

5,6,7,8-tetrahydrofolic acidReach from here →

Catalysed by DHFR, DHFR2cytosolOne of 3 routes

a dicarboxylateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

chlorine(.)Reach from here →

Catalysed by SLC22A8, SLC22A7, SLC26A6extracellular space, cytosol

D-aspartateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-aspartateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

oxalateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC26A2 and 3 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

maleateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

malonic acidReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A10extracellular space, cytosol, mitochondrial matrixOne of 2 routes

(2R,3R)-tartrateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

(S,S)-tartrateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

(3R)-citramalateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

(3S)-citramalateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

thiosulfateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 2 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

(6S)-5,6,7,8-tetrahydrofolateReach from here →

Catalysed by DHFR, DHFR2cytosol

N-sulfo-D-glucosamineReach from here →

Catalysed by SLC22A8, SLC22A7, SGSHextracellular space, cytosol

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol

adenosine 5'-phosphosulfateReach from here →

Catalysed by SLC22A8, SLC22A7, PAPSS1, PAPSS2extracellular space, cytosolOne of 4 routes

estrone 3-sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol

(5-hydroxyindol-3-yl)acetateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC4A1extracellular space, cytosolOne of 2 routes

SLC22A8

, SLC22A7

, SLC25A14

, SLC25A30

extracellular space, cytosol, inner side of the membrane, outer side of the membrane, mitochondrial matrix

CHEBI:1307929Reach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosol, Golgi apparatusOne of 4 routes

a quinoneReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A10, SDHBextracellular space, cytosol, mitochondrial matrix

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by SLC22A8, SLC22A7, STS, SLCO1B1extracellular space, cytosolOne of 4 routes

indoxyl sulfateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A35, SLC25A34 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

cholineReach from here →

Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC5A7extracellular space, cytosol

pyruvateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A10, ME2 and 1 moreextracellular space, cytosol, mitochondrial matrixOne of 7 routes

L-leucineReach from here →

Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosolOne of 4 routes

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateReach from here →

Catalysed by DHFR, DHFR2, SHMT1, SHMT2cytosolOne of 2 routes

10-formyltetrahydrofolic acidReach from here →

Catalysed by DHFR, DHFR2, MTHFD1cytosolOne of 3 routes

5-methyltetrahydrofolic acidReach from here →

Catalysed by DHFR, DHFR2, HNMTcytosol

formateReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC26A2 and 3 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

nicotinic acid D-ribonucleotideReach from here →

Catalysed by SLC22A8, SLC22A7, SLC22A6, QPRTextracellular space, cytosol

N-carbamoyl-L-aspartic acidReach from here →

Catalysed by SLC22A8, SLC22A7, SLC25A14, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane

CHEBI:15971Reach from here →

Catalysed by SLC22A8, SLC22A7, SLC26A6, SLC6A14extracellular space, cytosol

androsteroneReach from here →

Catalysed by SLC22A8, SLC22A7, STSextracellular space, cytosolOne of 3 routes